Literature DB >> 5057625

Nucleated assembly of microtubules in porcine brain extracts.

G G Borisy, J B Olmsted.   

Abstract

Disk-type structures found in extracts of porcine brain tissue appear to be required for microtubule assembly in vitro. From the morphology of the disks and the dependence of microtubule assembly on the presence of these structures, we propose that the disks are nucleation centers for the polymerization of microtubule protein.

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Year:  1972        PMID： 5057625     DOI： 10.1126/science.177.4055.1196

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  54 in total

1.  The role of microtubules in the assembly of vinblastine-induced crystals.

Authors:  H Stebbings
Journal:  Cell Tissue Res       Date:  1975-05-27       Impact factor: 5.249

2.  Control of microtubule assembly-disassembly by calcium-dependent regulator protein.

Authors:  J M Marcum; J R Dedman; B R Brinkley; A R Means
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

3.  Tubulin requires tau for growth onto microtubule initiating sites.

Authors:  G B Witman; D W Cleveland; M D Weingarten; M W Kirschner
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

4.  Assembly of chick brain tubulin onto flagellar microtubules from Chlamydomonas and sea urchin sperm.

Authors:  L I Binder; W L Dentler; J L Rosenbaum
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205

5.  A protein factor essential for microtubule assembly.

Authors:  M D Weingarten; A H Lockwood; S Y Hwo; M W Kirschner
Journal:  Proc Natl Acad Sci U S A       Date:  1975-05       Impact factor: 11.205

6.  Changes in microtubule phosphorylation during cell cycle of HeLa cells.

Authors:  R Piras; M M Piras
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205

7.  Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.

Authors:  R D Sloboda; S A Rudolph; J L Rosenbaum; P Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

8.  The fine structure of the centrohelidian heliozoan Heterophrys marina.

Authors:  C F Bardele
Journal:  Cell Tissue Res       Date:  1975-08-01       Impact factor: 5.249

9.  Stoichiometry of GTP hydrolysis and tubulin polymerization.

Authors:  R Maccioni; N W Seeds
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

Review 10.  Cell biology of leukocyte abnormalities--membrane and cytoskeletal function in normal and defective cells. A review.

Authors:  J M Oliver
Journal:  Am J Pathol       Date:  1978-10       Impact factor: 4.307
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