Literature DB >> 5055947

Control of carcinogenesis: a possible role for the activated macrophage.

J B Hibbs, L H Lambert, J S Remington.   

Abstract

Cytotoxic activity of activated mouse macrophages against mouse embryo fibroblasts was tested before and after spontaneous transformation of the fibroblasts in vitro. Activated macrophages caused little or no destruction of untransformed fibroblasts but were markedly cytotoxic to the same fibroblasts after spontaneous transformation. The efferent limb of this cytotoxic reaction appears to be nonimmunologic and to be related to abnormal growth properties rather than to the antigenic composition of target cells.

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Year:  1972        PMID： 5055947     DOI： 10.1126/science.177.4053.998

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  33 in total

1.  Effect of treatment with BCG on the course of visceral leishmaniasis in BALB/c mice.

Authors:  L L Smrkovski; C L Larson
Journal:  Infect Immun       Date:  1977-04       Impact factor: 3.441

2.  Macrophage-resistant murine simian virus 40 tumors express a retroviral type-specific gp70.

Authors:  S K Chapes; A E O'Neill; L Flaherty; L R Gooding
Journal:  J Virol       Date:  1987-03       Impact factor: 5.103

3.  Adjuvant immunotherapy with BCG in squamous-cell bronchial carcinoma. Immune-reactivity in relation to immunostimulation (preliminary results in a controlled trial).

Authors:  H M Jansen; T H The; G C de Gast; M T Esselink; A M van der Wal; N G Orie
Journal:  Thorax       Date:  1978-08       Impact factor: 9.139

4.  Testing monocyte function.

Authors: 
Journal:  Br Med J       Date:  1978-01-21

5.  An endotoxin-induced serum factor that causes necrosis of tumors.

Authors:  E A Carswell; L J Old; R L Kassel; S Green; N Fiore; B Williamson
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205

6.  Direct activation of the J774.1 Murine macrophage cell line by mycoplasma arthritidis.

Authors:  J N Dietz; B C Cole
Journal:  Infect Immun       Date:  1982-08       Impact factor: 3.441

7.  Characteristics of cells present in peritoneal fluids of mice injected intraperitoneally with Bordetella pertussis.

Authors:  C W Fishel; D G Halkias; T W Klein; A Szentivanyi
Journal:  Infect Immun       Date:  1976-01       Impact factor: 3.441

8.  TNF-alpha mediated selection of macrophage-resistant gene-regulatory tumor variants.

Authors:  L Remels; A Neirynck; L Brys; E Vercauteren; P De Baetselier
Journal:  Clin Exp Metastasis       Date:  1989 Sep-Oct       Impact factor: 5.150

9.  Development of functional diversity in mouse macrophages. Mutual exclusion of two phenotypic states.

Authors:  D J Laszlo; P M Henson; L K Remigio; L Weinstein; C Sable; P W Noble; D W Riches
Journal:  Am J Pathol       Date:  1993-08       Impact factor: 4.307

10.  Effect of colony stimulating factor on murine macrophages. Induction of antitumor activity.

Authors:  E J Wing; A Waheed; R K Shadduck; L S Nagle; K Stephenson
Journal:  J Clin Invest       Date:  1982-02       Impact factor: 14.808
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