Literature DB >> 5052733

Bone resorbing activity in supernatant fluid from cultured human peripheral blood leukocytes.

J E Horton, L G Raisz, H A Simmons, J J Oppenheim, S E Mergenhagen.   

Abstract

A new soluble mediator was found in supernatant fluid from cultures of human peripheral blood leukocytes that were stimulated by phytohemagglutinin, or by antigenic material present in human dental plaque deposits. This soluble Jactor produced bone resorption in organ cultures of fetal rat bones as measured by increased release of calcium-45, and also increased the number of active osteoclasts.

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Year:  1972        PMID： 5052733     DOI： 10.1126/science.177.4051.793

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  101 in total

1.  Progressin understanding periodontal disease.

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Journal:  Proc R Soc Med       Date:  1975-02

2.  Interactions between immune and bone cells: new insights with many remaining questions.

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3.  Effect of osteoclast activating factor from human leukocytes on bone metabolism.

Authors:  L G Raisz; R A Luben; G R Mundy; J W Dietrich; J E Horton; C L Trummel
Journal:  J Clin Invest       Date:  1975-08       Impact factor: 14.808

4.  Effects of osteoclast activating factor from human lymphocytes on cyclic AMP concentrations in isolated mouse bone and bone cells.

Authors:  R A Luben; M C Chen; D M Rosen; M A Mohler
Journal:  Calcif Tissue Int       Date:  1979-08-24       Impact factor: 4.333

5.  Studies on the pathogenesis of cancer hypercalcemia.

Authors:  W P Laird Myers; R Bockman
Journal:  Trans Am Clin Climatol Assoc       Date:  1977

Review 6.  Inflammatory osteolysis: a conspiracy against bone.

Authors:  Gabriel Mbalaviele; Deborah V Novack; Georg Schett; Steven L Teitelbaum
Journal:  J Clin Invest       Date:  2017-06-01       Impact factor: 14.808

7.  Stimulation of bone resorption by inflamed nasal mucosa, dermonecrotic toxin-containing conditioned medium from Pasteurella multocida, and purified dermonecrotic toxin from P. multocida.

Authors:  T G Kimman; C W Löwik; L J van de Wee-Pals; C W Thesingh; P Defize; E M Kamp; O L Bijvoet
Journal:  Infect Immun       Date:  1987-09       Impact factor: 3.441

8.  Partial purification of osteoclast-activating factor from phytohemagglutinin-stimulated human leukocytes.

Authors:  R A Luben; G R Mundy; C L Trummel; L G Raisz
Journal:  J Clin Invest       Date:  1974-05       Impact factor: 14.808

9.  Prostaglandins: bone resorption stimulating factors released from monkey gingiva.

Authors:  B D Gomes; E Hausmann; N Wienfeld; C De Luca
Journal:  Calcif Tissue Res       Date:  1976-03-31

10.  Cell-mediated immune response to products of Actinomyces viscosus cultures.

Authors:  D W Turner; B S Roberson; R W Longton
Journal:  Infect Immun       Date:  1976-08       Impact factor: 3.441
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