Literature DB >> 504988

Phenylethylamine in paranoid chronic schizophrenia.

S G Potkin, F Karoum, L W Chuang, H E Cannon-Spoor, I Phillips, R J Wyatt.   

Abstract

Phenylethylamine (PEA) is an endogenous amine that is structurally and pharmacologically related to amphetamine. Urinary PEA excretion is significantly higher in paranoid chronic schizophrenics than in nonparanoid chronic schizophrenics and normal controls. Diet, hospitalization, and medication do not account for differences in PEA concentrations. These findings offer some indication that PEA may be an endogenous amphetamine.

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Year:  1979        PMID: 504988     DOI: 10.1126/science.504988

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  22 in total

Review 1.  Receptors of mammalian trace amines.

Authors:  Anita H Lewin
Journal:  AAPS J       Date:  2006-03-10       Impact factor: 4.009

2.  S(+)amphetamine induces a persistent leak in the human dopamine transporter: molecular stent hypothesis.

Authors:  Aldo A Rodriguez-Menchaca; Ernesto Solis; Krasnodara Cameron; Louis J De Felice
Journal:  Br J Pharmacol       Date:  2012-04       Impact factor: 8.739

3.  New high-performance liquid chromatographic procedure for the detection and quantification of beta-phenylethylamine.

Authors:  F Gusovsky; K A Jacobson; K L Kirk; T Marshall; M Linnoila
Journal:  J Chromatogr       Date:  1987-03-20

4.  Behavioral sensitization to beta-phenylethylamine (PEA): enduring modifications of specific dopaminergic neuron systems in the rat.

Authors:  T Kuroki; T Tsutsumi; M Hirano; T Matsumoto; Y Tatebayashi; K Nishiyama; H Uchimura; A Shiraishi; T Nakahara; K Nakamura
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

5.  Inhibition of monoamine oxidases by haloperidol and its metabolites: pharmacological implications for the chemotherapy of schizophrenia.

Authors:  J Fang; P H Yu; J W Gorrod; A A Boulton
Journal:  Psychopharmacology (Berl)       Date:  1995-03       Impact factor: 4.530

6.  Urinary phenylethylamine correlates positively with hypomania, and negatively with depression, paranoia, and social introversion on the MMPI.

Authors:  H W Moises; P Waldmeier; H Beckmann
Journal:  Eur Arch Psychiatry Neurol Sci       Date:  1986

7.  A pharmacological analysis of the hyperactivity syndrome induced by beta-phenylethylamine in the mouse.

Authors:  C T Dourish
Journal:  Br J Pharmacol       Date:  1982-09       Impact factor: 8.739

8.  Electrophysiological Actions of Synthetic Cathinones on Monoamine Transporters.

Authors:  Ernesto Solis
Journal:  Curr Top Behav Neurosci       Date:  2017

Review 9.  Trace amine-associated receptor 1-Family archetype or iconoclast?

Authors:  David K Grandy
Journal:  Pharmacol Ther       Date:  2007-07-17       Impact factor: 12.310

10.  Phenylethylamine and monoamine metabolites in CSF of schizophrenics: effects of neuroleptic treatment.

Authors:  H Beckmann; P Waldmeier; J Lauber; W F Gattaz
Journal:  J Neural Transm       Date:  1983       Impact factor: 3.575

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