Literature DB >> 504557

Biological effects of negative pions in monolayers and spheroids of Chinese hamster cells.

K F Weibezahn, H Dertinger, H Schlag, C Lücke-Huhle.   

Abstract

The therapeutic value of pion irradiation was critically challenged by examining, in a cell culture system, various parameters of biological significance such as relative biological efficiency (RBE), oxygen enhancement ratio (OER), DNA-break formation, changes in cell cycle kinetics and regrowth. In all parameters, pions were superior to conventional low-LET radiation.

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Year:  1979        PMID: 504557     DOI: 10.1007/bf01358289

Source DB:  PubMed          Journal:  Radiat Environ Biophys        ISSN: 0301-634X            Impact factor:   1.925


  10 in total

1.  A comparative study of post-irradiation growth kinetics of spheroids and monolayers.

Authors:  H Dertinger; C Lücke Huhle
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1975-09

2.  Negative pion irradiation of mammalian cells. 1. Survival characteristics of monolayers and spheroids of Chinese hamster lung cells.

Authors:  H Dertinger; C Lücke-Huhle; H Schlag; K F Weibezahn
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1976-03

3.  [Dosimetry of negative pi-mesons (author's transl)].

Authors:  K F Weibezahn; P Kindermann; T Mohr
Journal:  Strahlentherapie       Date:  1977-10

4.  Negative pion irradiation of mammalian cells. II. A comparative analysis of cell-cycle progression after exposure to pi-mesons and cobalt gamma-rays.

Authors:  H Schlag; K F Weibezahn; C Lücke-Huhle
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1978-01

5.  The results of fast neutron therapy from the Medical Research Council's cyclotron at Hammersmith hospital, London, with particular reference to tumours of the head and neck.

Authors:  M Catterall
Journal:  Strahlentherapie       Date:  1974-11

6.  Radiation induced strand breakage in DNA from mammalian cells. Strand separation in alkaline solution.

Authors:  G Ahnström; K Erixon
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1973-03

7.  Kinetic response of an in vitro "tumour-model" (V 79 spheroids) to 42 degrees C hyperthermia.

Authors:  C Lücke-Huhle; H Dertinger
Journal:  Eur J Cancer       Date:  1977-01       Impact factor: 9.162

8.  Negative pion irradiation of mammalian cells. III. A comparative analysis of DNA strand breakage, repair and cell survival after exposure to pi-mesons and X-rays.

Authors:  K F Weibezahn; C Sexauer; T Coquerelle
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1980-10

9.  Kinetics of regrowth of V79 spheroids after gamma- and pi--irradiation.

Authors:  H Dertinger
Journal:  Strahlentherapie       Date:  1979-10

10.  Differential radiosensitivity of two mammalian cell lines after hyperthermic pretreatment.

Authors:  C Lücke-Huhle; H Schlag
Journal:  Strahlentherapie       Date:  1979-09
  10 in total
  1 in total

Review 1.  Multicellular spheroids. A review on cellular aggregates in cancer research.

Authors:  W Mueller-Klieser
Journal:  J Cancer Res Clin Oncol       Date:  1987       Impact factor: 4.553

  1 in total

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