Literature DB >> 504267

Limulus amebocyte lysate - a means to monitor inactivation of lipopolysaccharide.

K Tsuji, S J Harrison.   

Abstract

A properly selected Limulus Amebocyte Lysate (LAL) has been demonstrated to have a good correlation with the in vivo United States Pharmacopeial pyrogen test when testing lipopolysaccharide (LPS) inactivated with ethylene oxide, 60 Co irradiation, and dry-heat treatments. Thus, LAL may be used to determine degradation or depyrogenation kinetics of LPS. A criteria for acceptance of an LAL lot for correlation with the USP pyrogen test is described.

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Year:  1979        PMID： 504267

Source DB:  PubMed          Journal:  Prog Clin Biol Res        ISSN： 0361-7742


  5 in total

1.  Endotoxin removal from water using microporous polyethylene chopped fibres as a new adsorbent.

Authors:  Y Sawada; R Fujii; I Igami; A Kawai; T Kamiki; M Niwa
Journal:  J Hyg (Lond)       Date:  1986-08

2.  Removal of endotoxin from water by microfiltration through a microporous polyethylene hollow-fiber membrane.

Authors:  Y Sawada; R Fujii; I Igami; A Kawai; T Kamiki; M Niwa
Journal:  Appl Environ Microbiol       Date:  1986-04       Impact factor: 4.792

3.  Sensitivity, specificity, and predictive values of the Limulus lysate assay for detection of exclusion of gonococcal cervicitis.

Authors:  V A Spagna; R B Prior; G A Sawaya
Journal:  J Clin Microbiol       Date:  1982-07       Impact factor: 5.948

4.  Turbidimetric method for quantifying serum inhibition of Limulus amoebocyte lysate.

Authors:  T J Novitsky; P F Roslansky; G R Siber; H S Warren
Journal:  J Clin Microbiol       Date:  1985-02       Impact factor: 5.948

5.  Improved utility of Gonoscreen, a Limulus amoebocyte lysate assay, in the evaluation of urethral discharges in men.

Authors:  R B Prior; V A Spagna
Journal:  J Clin Microbiol       Date:  1985-08       Impact factor: 5.948
  5 in total

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