Literature DB >> 5040664

Morphine hyperthermia in the rat: its attenuation by physostigmine.

M Sharkawi.   

Abstract

1. In rats, a subcutaneous injection of morphine (2.5 mg/kg) produced hyperthermia which was greatly attenuated by an intraperitoneal injection of physostigmine (0.1 mg/kg), but not of neostigmine (0.08 mg/kg) and promptly reversed by a subcutaneous injection of nalorphine.2. It is concluded that the hyperthermia is a specific response to morphine, central in origin, and the result of diminished acetylcholine (ACh) release from central cholinergic neurones.

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Year:  1972        PMID： 5040664      PMCID： PMC1665827          DOI： 10.1111/j.1476-5381.1972.tb07291.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  11 in total

1.  DEPRESSION BY MORPHINE AND CHLORALOSE OF ACETYLCHOLINE RELEASE FROM THE CAT'S BRAIN.

Authors:  D BELESLIN; R L POLAK
Journal:  J Physiol       Date:  1965-04       Impact factor: 5.182

2.  The temperature response in rats during acute and chronic morphine administration, a study of morphine tolerance.

Authors:  L M GUNNE
Journal:  Arch Int Pharmacodyn Ther       Date:  1960-12-31

3.  The relationship between skin temperature and the effect of morphine upon the response to thermal stimuli in the albino rat and the dog.

Authors:  C A WINTER; L FLATAKER
Journal:  J Pharmacol Exp Ther       Date:  1953-10       Impact factor: 4.030

4.  Inhibition by morphine of the release of [14c]acetylcholine from rat brain cortex slices.

Authors:  M Sharkawi; M P Schulman
Journal:  J Pharm Pharmacol       Date:  1969-08       Impact factor: 3.765

5.  Temperature changes following iontophoretic injection of acetylcholine into the rostral hypothalamus of the rat.

Authors:  W E Kirkpatrick; P Lomax
Journal:  Neuropharmacology       Date:  1970-05       Impact factor: 5.250

6.  Effect on body temperature of morphine and ergotamine injected into the cerebral ventricles of cats.

Authors:  U Banerjee; W Feldberg; V J Lotti
Journal:  Br J Pharmacol Chemother       Date:  1968-03

7.  Effects of morphine and its antagonists on release of cerebral cortical acetylcholine.

Authors:  K Jhamandas; C Pinsky; J W Phillis
Journal:  Nature       Date:  1970-10-10       Impact factor: 49.962

8.  Temperature responses in the rat following intracerebral microinjection of morphine.

Authors:  V J Lotti; P Lomax; R George
Journal:  J Pharmacol Exp Ther       Date:  1965-10       Impact factor: 4.030

9.  The effect of atropine on the body temperature of the rat following systemic and intracerebral injection.

Authors:  W E Kirkpatrick; P Lomax
Journal:  Life Sci       Date:  1967-11-01       Impact factor: 5.037

10.  Inhibition by morphine of the release of acetylcholine from the intestine of the guinea-pig.

Authors:  W SCHAUMANN
Journal:  Br J Pharmacol Chemother       Date:  1957-03
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  7 in total

1.  Response of nigral dopamine neurons to actue and prolonged morphine treatment: effect of exposure to cold, physostigmine and nicotine.

Authors:  R Lienhart; W Lichtensteiger; H Langemann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

2.  Entanglement between thermoregulation and nociception in the rat: the case of morphine.

Authors:  Nabil El Bitar; Bernard Pollin; Elias Karroum; Ivanne Pincedé; Daniel Le Bars
Journal:  J Neurophysiol       Date:  2016-09-07       Impact factor: 2.714

3.  Physostigmine attenuation of delta 9-tetrahydrocannabinol induced hyperthermia in rats.

Authors:  J O Johansson; T U Järbe; B G Henriksson
Journal:  Experientia       Date:  1974-07-15

4.  Endorphin-induced hyperthermia: characterization of the exogenously and endogenously induced effects.

Authors:  J Bläsig; U Bäuerle; A Herz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-11       Impact factor: 3.000

5.  Role of brain catecholamines and 5-hydroxytryptamine in morphine induced temperature changes in normal and tolerant rats and mice.

Authors:  P Slater; C Blundell
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-08       Impact factor: 3.000

6.  Inhibition by cholinergic agonists of the prolactin release induced by morphine.

Authors:  T Muraki; Y Tokunaga; T Nakadate; R Kato
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-09       Impact factor: 3.000

7.  Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1).

Authors:  Tatjana Meyer; Nikolaus Jahn; Stefanie Lindner; Linda Röhner; Anna Dolnik; Daniela Weber; Annika Scheffold; Simon Köpff; Peter Paschka; Verena I Gaidzik; Dirk Heckl; Sebastian Wiese; Benjamin L Ebert; Hartmut Döhner; Lars Bullinger; Konstanze Döhner; Jan Krönke
Journal:  Leukemia       Date:  2019-10-01       Impact factor: 11.528
  7 in total

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