| Literature DB >> 5035472 |
Abstract
The extracellular space of the rat brain was visualized by electron roscopy in sections of cerebral cortex fixed by freeze-substitution. The volume tissue occupied by the extracellular space was estimated stereomnetrically, and found to decrease from 20.8 percent in 3-month-old rats to 9.6 percent in escent animals, 26 months of age. This decrease in extracellular space indicates age-associated change in the microenvironment of nerve cells.Entities:
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Year: 1972 PMID: 5035472 DOI: 10.1126/science.176.4039.1135
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728