Cytochalasin B: inhibition of D-2-deoxyglucose transport into leukocytes and fibroblasts.

Cytochalasin B inhibits transport of (D)-2-deoxyglucose and of glucosamine into kukocytes, but does not impair uptake of kucine by these cells. This inhibitory action is rapid and reversible, and results in suppression of glycolysis. Cytochalasin B also blocks transport of (D)-2-deoxyglucose, but not of leucine, into mouse L strain fibroblasts.