| Literature DB >> 5032356 |
Abstract
The number of synapses in the molecular layer of the rat cerebellum is reduced by early hypo-and hyperthyroidism within 30 days. Hypothyroidism retards synaptogenesis after 10 days, while hyperthyroidism accelerates synaptogenesis initially, but by 21 days the number of synapses is reduced. The sensitivity of developing synapses to thyroid hormone may permit analysis of the events triggering synaptogenesis.Entities:
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Year: 1972 PMID: 5032356 DOI: 10.1126/science.176.4034.530
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728