Literature DB >> 5031658

Role of third serum vitamin B 12 binding protein in vitamin B 12 transport.

I Chanarin, J M England, K L Rowe, J A Stacey.   

Abstract

A third vitamin B(12) binding protein present in normal serum has been shown to participate in transport of labelled vitamin B(12) absorbed from the gut. All three vitamin B(12) binding proteins in serum were labelled at the same time after oral administration of vitamin B(12), implying that "free" vitamin B(12) reached the portal blood from the gut mucosa.

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Year:  1972        PMID： 5031658      PMCID： PMC1788068          DOI： 10.1136/bmj.2.5811.441

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  7 in total

1.  THE DYNAMICS OF TRANSCOBALAMIN II. A VITAMIN B12 BINDING SUBSTANCE IN PLASMA.

Authors:  C A HALL; A E FINKLER
Journal:  J Lab Clin Med       Date:  1965-03

2.  The heterogeneity of the high molecular weight B12 binder in serum.

Authors:  C Lawrence
Journal:  Blood       Date:  1969-06       Impact factor: 22.113

3.  Identification of a new vitamin B 12 binder (transcobalamin 3) in normal human serum.

Authors:  F J Bloomfield; J M Scott
Journal:  Br J Haematol       Date:  1972-01       Impact factor: 6.998

4.  A 57Co vitamin B12 binder in normal serum eluted by DEAE-cellulose chromatography with 0. 1m sodium phosphate buffer, pH 5.8.

Authors:  E J Gizis; M F Dietrich; G Ohoi; L M Meyer
Journal:  J Lab Clin Med       Date:  1970-04

5.  A vitamin B 12 binding protein in polycythemia vera plasma.

Authors:  C A Hall; A E Finkler
Journal:  Biochim Biophys Acta       Date:  1967-09-19

6.  Demonstration of transcobalamin II complex formation and binding to Sephadex G-200 at low ionic strength.

Authors:  B L Hom
Journal:  Clin Chim Acta       Date:  1967-11       Impact factor: 3.786

7.  Vitamin B 12 -binding protein abnormality in subjects without myeloproliferative disease. II. The presence of a third vitamin B 12 -binding protein in serum.

Authors:  R Carmel
Journal:  Br J Haematol       Date:  1972-01       Impact factor: 6.998
  7 in total
  3 in total

1.  Levels in normal, pathological, and foetal sera of the three transcobalamins.

Authors:  F J Bloomfield; J M Scott; J J Somerville; D G Weir
Journal:  Ir J Med Sci       Date:  1973-03       Impact factor: 1.568

2.  [Vitamin B12 binding glycoproteins. VIIth. Unsaturated 57Co-cyanocobalamin binding capacity of glycoproteins in chronic myelogenous leukaemia (author's transl)].

Authors:  G Haffner; E Kallee
Journal:  Klin Wochenschr       Date:  1973-07-15

3.  Studies on derivation of transcobalamin 3 from granulocytes. Enhancement by lithium and elimination by fluoride of in vitro increments in vitamin B12-binding capacity.

Authors:  J M Scott; F J Bloomfield; R Stebbins; V Herbert
Journal:  J Clin Invest       Date:  1974-01       Impact factor: 14.808
  3 in total

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