Literature DB >> 5027639

The influence of drugs upon the anticoagulant activity of heparin.

E D Hodby, J Hirsh, C Adeniyi-Jones.   

Abstract

Although physical incompatibility between heparin and a number of drugs has been reported we did not discover any evidence of such incompatibility when heparin was mixed with 11 commonly used drugs in therapeutic concentrations.Furthermore, there was no detectable change in the anticoagulant activity in the presence of any of these drugs, nor was there any change in the biological activity of the antibiotics tested.

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Year:  1972        PMID: 5027639      PMCID: PMC1940461     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  9 in total

1.  STABILITY OF HEPARIN SOLUTIONS.

Authors:  J PRITCHARD
Journal:  J Pharm Pharmacol       Date:  1964-07       Impact factor: 3.765

2.  Heparin metabolism: isolation and characterization of uroheparin.

Authors:  B M McAllister; D J Demis
Journal:  Nature       Date:  1966-10-15       Impact factor: 49.962

3.  Heparin: molecular weight and degradation studies.

Authors:  E Braswell
Journal:  Biochim Biophys Acta       Date:  1968-04-16

Review 4.  Treatment of pulmonary embolic disease. A critical review of some aspects of current therapy.

Authors:  D P Thomas
Journal:  N Engl J Med       Date:  1965-10-21       Impact factor: 91.245

5.  The activated partial thromboplastin time in the control of heparin treatment.

Authors:  J Hirsh; E F O'Sullivan; A S Gallus; M Martin
Journal:  Australas Ann Med       Date:  1970-11

6.  Problems with intravenous additives.

Authors:  G M Eckert; B W Gunner
Journal:  Australas Ann Med       Date:  1970-11

7.  Current concepts: the use of heparin.

Authors:  D Deykin
Journal:  N Engl J Med       Date:  1969-04-24       Impact factor: 91.245

8.  Extemporaneous sterile compounding of intravenous additives.

Authors:  J M Meisler; M W Skolaut
Journal:  Am J Hosp Pharm       Date:  1966-10

9.  Some incompatibilities of intravenous admixtures.

Authors:  T J Fowler
Journal:  Am J Hosp Pharm       Date:  1967-08
  9 in total
  2 in total

1.  Heparin stability: effects of diluent, heparin activity, container, and pH.

Authors:  K T Goodall; C C Chooi; A S Gallus
Journal:  J Clin Pathol       Date:  1980-12       Impact factor: 3.411

Review 2.  Antithrombotic drugs: part I.

Authors:  A S Gallus; J Hirsh
Journal:  Drugs       Date:  1976       Impact factor: 9.546

  2 in total

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