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Literature DB >> 50254

Antibodies to double-stranded (native) DNA in active chronic hepatitis.

Abstract

Sera from 36 patients with active chronic hepatitis were studied for the presence of antibodies to double-stranded (native) DNA. These antibodies are a specific antinuclear antibody previously shown to have a high degree of specificity for systemic lupus erythematosus. Fifteen of the 36 patients (42%) were found to have levels of antibody usually only reported in systemic lupus erythematosus and higher than those seen in a control population. Anti-DNA antibodies were not found in a group of 22 patients with other forms of liver disease.

Entities: Disease Species

Mesh：

Substances：

Year: 1975 PMID： 50254 PMCID： PMC1411032 DOI： 10.1136/gut.16.6.413

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

8 in total

1. ACTIVE 'JUVENILE' CIRRHOSIS CONSIDERED AS PART OF A SYSTEMIC DISEASE AND THE EFFECT OF CORTICOSTEROID THERAPY.

Authors: A E READ; S SHERLOCK; C V HARRISON
Journal: Gut Date: 1963-12 Impact factor: 23.059

2. Significance of anti-D.N.A. antibodies in systemic lupus erythematosus.

Authors: G R Hughes
Journal: Lancet Date: 1971-10-16 Impact factor: 79.321

3. Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid.

Authors: R T Wold; F E Young; E M Tan; R S Farr
Journal: Science Date: 1968-08-23 Impact factor: 47.728

4. Immunologic and viral factors in the pathogenesis of systemic lupus erythematosus.

Authors: N Talal
Journal: Arthritis Rheum Date: 1970 Nov-Dec

5. Arthritis in acute hepatitis and chronic active hepatitis. Pathology of the synovial membrane with evidence for the presence of Australia antigen in synovial membranes.

Authors: H R Schumacher; E P Gall
Journal: Am J Med Date: 1974-10 Impact factor: 4.965

6. Anti-DNA activity in systemic lupus erythematosus. A diagnostic and therapeutic guide.

Authors: G R Hughes; S A Cohen; C L Christian
Journal: Ann Rheum Dis Date: 1971-05 Impact factor: 19.103

7. Double-stranded RNA antibodies in systemic lupus erythematosus.

Authors: P Davis; P Cunnington; G R Hughes
Journal: Ann Rheum Dis Date: 1975-06 Impact factor: 19.103

8. Renal tubular acidosis and autoimmune liver disease.

Authors: P L Golding; A S Mason
Journal: Gut Date: 1971-02 Impact factor: 23.059

8 in total

12 in total

10. Detection of anti-double and anti-single stranded DNA antibodies in chronic liver disease: significance of anti-double stranded DNA antibody in autoimmune hepatitis.

Authors: K Tsuchiya; K Kiyosawa; H Imai; T Sodeyama; S Furuta
Journal: J Gastroenterol Date: 1994-04 Impact factor: 7.527

Antibodies to double-stranded (native) DNA in active chronic hepatitis.

1. ACTIVE 'JUVENILE' CIRRHOSIS CONSIDERED AS PART OF A SYSTEMIC DISEASE AND THE EFFECT OF CORTICOSTEROID THERAPY.

2. Significance of anti-D.N.A. antibodies in systemic lupus erythematosus.

3. Deoxyribonucleic acid antibody: a method to detect its primary interaction with deoxyribonucleic acid.

4. Immunologic and viral factors in the pathogenesis of systemic lupus erythematosus.

5. Arthritis in acute hepatitis and chronic active hepatitis. Pathology of the synovial membrane with evidence for the presence of Australia antigen in synovial membranes.

6. Anti-DNA activity in systemic lupus erythematosus. A diagnostic and therapeutic guide.

7. Double-stranded RNA antibodies in systemic lupus erythematosus.

8. Renal tubular acidosis and autoimmune liver disease.

1. DNA-binding antibodies and hepatitis B markers in acute and chronic liver disease.

2. Functional effects of CRP binding to nuclei.

Review 3. Anti-DNA antibodies. Their idiotypes and SLE.

4. Double-stranded DNA-binding capacity of serum in acute and chronic liver disease.

5. Single stranded DNA binding antibodies in patients with obstructive jaundice.

6. Measurement of serum DNA binding in chronic active hepatitis and systemic lupus erythematosus using the Farr assay.

7. Chronic active hepatitis with high level of anti-ds-DNA detected by a solid phase radioimmunoassay.

8. Antibody to synthetic poly dAT: correlation with antibody to native DNA and specificity for SLE.

9. Autoimmune chronic active hepatitis developing after acute type B hepatitis.

10. Detection of anti-double and anti-single stranded DNA antibodies in chronic liver disease: significance of anti-double stranded DNA antibody in autoimmune hepatitis.