Literature DB >> 5019790

Immunologic tolerance: role of the regional lymph node.

M H Friedlaender, H Baer.   

Abstract

Dansyl chloride, a skin setnsitizer when injected in complete Freund's adjuvant, induced marked tolerance and no sensitization when applied to the intact skin of guinea pigs. Application of this chemical to alymphatic skin islands failed to induce tolerance or sensitization. Lymnphatic connections between skin and regional lymph nodes were essential for the developmnent of ismmunologic toleance.

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Year:  1972        PMID： 5019790     DOI： 10.1126/science.176.4032.312

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

Review 1.  Lymphatic and interstitial flow in the tumour microenvironment: linking mechanobiology with immunity.

Authors:  Melody A Swartz; Amanda W Lund
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Review 2.  Implications of Lymphatic Transport to Lymph Nodes in Immunity and Immunotherapy.

Authors:  Susan N Thomas; Nathan A Rohner; Erin E Edwards
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Review 3.  Emerging roles of lymphatic endothelium in regulating adaptive immunity.

Authors:  Catherine M Card; Shann S Yu; Melody A Swartz
Journal:  J Clin Invest       Date:  2014-03-03       Impact factor: 14.808

4.  Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells.

Authors:  Sachiko Hirosue; Efthymia Vokali; Vidya R Raghavan; Marcela Rincon-Restrepo; Amanda W Lund; Patricia Corthésy-Henrioud; Francesca Capotosti; Cornelia Halin Winter; Stéphanie Hugues; Melody A Swartz
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6.  Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage.

Authors:  Susan N Thomas; Joseph M Rutkowski; Miriella Pasquier; Emma L Kuan; Kari Alitalo; Gwendalyn J Randolph; Melody A Swartz
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Review 7.  The Role of the Tumor Vasculature in the Host Immune Response: Implications for Therapeutic Strategies Targeting the Tumor Microenvironment.

Authors:  Shona A Hendry; Rae H Farnsworth; Benjamin Solomon; Marc G Achen; Steven A Stacker; Stephen B Fox
Journal:  Front Immunol       Date:  2016-12-20       Impact factor: 7.561

Review 8.  Two Birds, One Stone: Double Hits on Tumor Growth and Lymphangiogenesis by Targeting Vascular Endothelial Growth Factor Receptor 3.

Authors:  Ming-Chuan Hsu; Mei-Ren Pan; Wen-Chun Hung
Journal:  Cells       Date:  2019-03-21       Impact factor: 6.600

Review 9.  Lymphatic Function in Autoimmune Diseases.

Authors:  Noa Schwartz; Madhavi Latha S Chalasani; Thomas M Li; Zhonghui Feng; William D Shipman; Theresa T Lu
Journal:  Front Immunol       Date:  2019-03-20       Impact factor: 7.561

10.  An integrin/MFG-E8 shuttle loads HIV-1 viral-like particles onto follicular dendritic cells in mouse lymph node.

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  10 in total

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