| Literature DB >> 5018056 |
Abstract
X-irradiation up to 480 R does not inhibit either adoptive transfer of delayed hypersensitivity or production in vitro of soluble mediators, such as migration-inhibitory factor (MIF). Above that dosage and as high as 3000 R, adoptive transfer is inhibited, but production of MIF is not. An increase in skin response occurred when 24-48 hr were allowed to elapse after intravenous transfer and before skin testing. Treatment of recipients with colchicine at the time of adoptive transfer inhibited the development of a skin reaction to specific antigen.Entities:
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Year: 1972 PMID: 5018056 PMCID: PMC2139154 DOI: 10.1084/jem.135.4.985
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307