Literature DB >> 5017305

Protection of rat bronchial epithelium against tobacco smoke.

R Jones, P Bolduc, L Reid.   

Abstract

Addition to tobacco of phenylmethyloxadiazole (PMO) protects rats against some of the adverse effects of exposure to cigarette smoke. Two groups of 15 rats were exposed to 25 cigarettes a day for 24 days; the group whose cigarette included PMO showed less immediate distress after exposure, a smaller tracheal goblet cell count, less thickening of the tracheal epithelium, and less cells in mitosis than those exposed to ordinary tobacco.

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Year:  1972        PMID： 5017305      PMCID： PMC1787987          DOI： 10.1136/bmj.2.5806.142

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  7 in total

1.  EMPHYSEMA AFTER LOW-LEVEL EXPOSURE TO NO2.

Authors:  G FREEMAN; G B HAYDON
Journal:  Arch Environ Health       Date:  1964-01

2.  Regeneration of tracheal epithelium.

Authors:  D L WILHELM
Journal:  J Pathol Bacteriol       Date:  1953-04

3.  Effect of extremes of temperature and humidity on the goblet cell count in the rat airway epithelium.

Authors:  R Jones; A M Baetjer; L Reid
Journal:  Br J Ind Med       Date:  1971-10

4.  Mitotic rates, goblet cell increase and histochemical changes in mucus in rat bronchial epithelium during exposure to sulphur dioxide.

Authors:  D Lamb; L Reid
Journal:  J Pathol Bacteriol       Date:  1968-07

5.  Evaluation of model systems for study of airway epithelium, cilia, and mucus.

Authors:  L Reid
Journal:  Arch Intern Med       Date:  1970-09

6.  Inhibition of the ciliostatic effect of cigarette smoke by oxolamine citrate.

Authors:  T Dalhamn
Journal:  Am Rev Respir Dis       Date:  1966-11

7.  Smoking risks of different tobaccos.

Authors:  R D Passey; M Blackmore; D Warbrick-Smith; R Jones
Journal:  Br Med J       Date:  1971-10-23
  7 in total
  8 in total

1.  Objectivity and quantification in lung disease.

Authors:  L Reid
Journal:  Postgrad Med J       Date:  1975-10       Impact factor: 2.401

2.  Goblet cell glycoprotein and tracheal gland hypertrophy in rat airways: the effect of tobacco smoke with or without the anti-inflammatory agent phenylmethyloxadiazole.

Authors:  R Jones; P Bolduc; L Reid
Journal:  Br J Exp Pathol       Date:  1973-04

3.  The effect of isoprenaline and pilocarpine on (a) bronchial mucus-secreting tissue and (b) pancreas, salivary glands, heart, thymus, liver and spleen.

Authors:  J Sturgess; L Reid
Journal:  Br J Exp Pathol       Date:  1973-08

Review 4.  Animal models of chronic obstructive pulmonary disease.

Authors:  Joanne L Wright; Manuel Cosio; Andrew Churg
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2008-05-02       Impact factor: 5.464

5.  The combined effects of vitamin A-deficiency and cigarette smoke on rat tracheal epithelium.

Authors:  P A Shields; P K Jeffery
Journal:  Br J Exp Pathol       Date:  1987-10

6.  Mitotic activity of airway epithelium after short exposure to tobacco smoke and the effect of the anti-inflammatory agent phenylmethyloxadiazole.

Authors:  P Bolduc; R Jones; L Reid
Journal:  Br J Exp Pathol       Date:  1981-10

7.  Hypersecretion of mucus glycoproteins in rat airways induced by tobacco smoke.

Authors:  S J Coles; L R Levine; L Reid
Journal:  Am J Pathol       Date:  1979-03       Impact factor: 4.307

8.  Mucous membrane of respiratory epithelium.

Authors:  L M Reid; R Jones
Journal:  Environ Health Perspect       Date:  1980-04       Impact factor: 9.031
  8 in total

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