Literature DB >> 501548

Resolution of (+/-)-propranolol.

Y Yost, J L Holtzman.   

Abstract

Two improvements in propranolol resolution were developed. Both the (+)- and (-)-di-(p-toluoyl)tartaric acids were used as the resolving agents. This procedure reduced the number of crystallizations needed to obtain a pure product. Furthermore, synthesis of the resolving agent was improved.

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Year:  1979        PMID: 501548     DOI: 10.1002/jps.2600680935

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  1 in total

1.  The influence of gender and sex steroid hormones on the plasma binding of propranolol enantiomers.

Authors:  U K Walle; T C Fagan; M J Topmiller; E C Conradi; T Walle
Journal:  Br J Clin Pharmacol       Date:  1994-01       Impact factor: 4.335

  1 in total

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