Comparison of 9 methods for the determination of cholesterol.

Seven enzymatic procedures for the determination of cholesterol in serum were compared with the Liebermann-Burchard- and a gas-chromatographic method. Using a decision matrix all methods could be ranked according to reliability and practicability . With the exception of the cholesterol oxidase-coupled Kageyama principle and the Liebermann-Burchard procedure, all the other methods showed similar reliability.