Literature DB >> 5010683

The tissue distribution, metabolism and excretion of lidocaine in rats, guinea pigs, dogs and man.

J B Keenaghan, R N Boyes.   

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Year:  1972        PMID： 5010683

Source DB:  PubMed          Journal:  J Pharmacol Exp Ther        ISSN： 0022-3565            Impact factor:   4.030


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  34 in total

1.  A comparative investigation of hepatic clearance models: predictions of metabolite formation and elimination.

Authors:  M V St-Pierre; P I Lee; K S Pang
Journal:  J Pharmacokinet Biopharm       Date:  1992-04

Review 2.  Clinical pharmacokinetics of local anaesthetics.

Authors:  G T Tucker; L E Mather
Journal:  Clin Pharmacokinet       Date:  1979 Jul-Aug       Impact factor: 6.447

3.  The impairment of lignocaine clearance by propranolol--major contribution from enzyme inhibition.

Authors:  N D Bax; G T Tucker; M S Lennard; H F Woods
Journal:  Br J Clin Pharmacol       Date:  1985-05       Impact factor: 4.335

4.  Effect of the CYP3A4 inhibitor erythromycin on the pharmacokinetics of lignocaine and its pharmacologically active metabolites in subjects with normal and impaired liver function.

Authors:  Rocco Orlando; Pierpaolo Piccoli; Sara De Martin; Roberto Padrini; Pietro Palatini
Journal:  Br J Clin Pharmacol       Date:  2003-01       Impact factor: 4.335

5.  The effect of liver disease and food on plasma MEGX concentrations.

Authors:  R Pritchard-Davies; A S Gross; G M Shenfield
Journal:  Br J Clin Pharmacol       Date:  1994-03       Impact factor: 4.335

6.  The pharmacokinetics and metabolism of the anilide local anaesthetics in neonates. I. Lignocaine.

Authors:  G W Mihaly; R G Moore; J Thomas; E J Triggs; D Thomas; C A Shanks
Journal:  Eur J Clin Pharmacol       Date:  1978-05-17       Impact factor: 2.953

Review 7.  Clinical pharmacokinetics of lignocaine.

Authors:  N L Benowitz; W Meister
Journal:  Clin Pharmacokinet       Date:  1978 May-Jun       Impact factor: 6.447

Review 8.  Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure.

Authors:  D E Drayer
Journal:  Clin Pharmacokinet       Date:  1976 Nov-Dec       Impact factor: 6.447

9.  Quantification of three lidocaine metabolites and their conjugates.

Authors:  Y K Tam; J Ke; R T Coutts; D G Wyse; M R Gray
Journal:  Pharm Res       Date:  1990-05       Impact factor: 4.200

10.  An enzyme-distributed system for lidocaine metabolism in the perfused rat liver preparation.

Authors:  K S Pang; J A Terrell; S D Nelson; K F Feuer; M J Clements; L Endrenyi
Journal:  J Pharmacokinet Biopharm       Date:  1986-04
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