Literature DB >> 5005719

A double-blind trial of disodium cromoglycate (Intal) in the treatment of bronchial asthma.

M Chan-Yeung, J Morton, S Grzybowski.   

Abstract

The result of a double-blind crossover trial with disodium cromoglycate (Intal) in 22 patients, nine with extrinsic asthma and 13 with intrinsic asthma, is reported. While eight extrinsic asthmatics showed considerable symptomatic improvement, only five of the intrinsic group improved while on disodium cromoglycate. Twelve out of 13 patients with symptomatic improvement had associated decrease in airway obstruction as measured by the FEV(1).It is concluded that disodium cromoglycate is useful in the treatment of asthma, particularly of the extrinsic type.

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Year:  1971        PMID: 5005719      PMCID: PMC1931207     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  7 in total

1.  Improvement in bronchial asthma not reflected in forced expiratory volume.

Authors:  A J Woolcock; J Read
Journal:  Lancet       Date:  1965-12-25       Impact factor: 79.321

2.  A double-blind trial of disodium cromoglycate in the treatment of allergic bronchial asthma.

Authors:  J B Howell; R E Altounyan
Journal:  Lancet       Date:  1967-09-09       Impact factor: 79.321

3.  Disodium cromoglycate in the treatment of bronchial asthma.

Authors:  P H Kidner; P Meisner; N B Pride; R S Pearson
Journal:  Lancet       Date:  1968-09-21       Impact factor: 79.321

4.  Clinical trial of disodium cromoglycate in treatment of asthma in children.

Authors:  J M Smith; G F Devey
Journal:  Br Med J       Date:  1968-05-11

5.  Effect of disodium cromoglycate on exercise-induced asthma.

Authors:  S E Davies
Journal:  Br Med J       Date:  1968-09-07

6.  Steroid-sparing effect of disodium cromoglycate ("Intal") in chronic asthma.

Authors:  J Read; A S Rebuck
Journal:  Med J Aust       Date:  1969-03-15       Impact factor: 7.738

7.  Disodium cromoglycate (FPL 670) ('Intal'): a specific inhibitor of reaginic antibody-antigen mechanisms.

Authors:  J S Cox
Journal:  Nature       Date:  1967-12-30       Impact factor: 49.962

  7 in total
  5 in total

1.  Editorial: New developments in the treatment of bronchial asthma.

Authors:  W A Mahon
Journal:  Can Med Assoc J       Date:  1974-02-16       Impact factor: 8.262

Review 2.  Disodium cromoglycate in allergic respiratory disease.

Authors: 
Journal:  Br Med J       Date:  1972-04-15

Review 3.  Sodium cromoglycate (cromolyn sodium): a review of its mode of action, pharmacology, therapeutic efficacy and use.

Authors:  R N Brogden; T M Speight; G S Avery
Journal:  Drugs       Date:  1974       Impact factor: 9.546

Review 4.  Inhaled cromones for prolonged non-specific cough in children.

Authors:  A Chang; J M Marchant; M McKean; P Morris
Journal:  Cochrane Database Syst Rev       Date:  2004

5.  An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate.

Authors:  Jamie Zagozewski; Ghazaleh M Shahriary; Ludivine Coudière Morrison; Olivier Saulnier; Margaret Stromecki; Agnes Fresnoza; Gareth Palidwor; Christopher J Porter; Antoine Forget; Olivier Ayrault; Cynthia Hawkins; Jennifer A Chan; Maria C Vladoiu; Lakshmikirupa Sundaresan; Janilyn Arsenio; Michael D Taylor; Vijay Ramaswamy; Tamra E Werbowetski-Ogilvie
Journal:  Nat Commun       Date:  2020-07-20       Impact factor: 14.919

  5 in total

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