Literature DB >> 5005518

Glibenclamide therapy in diabetes mellitus.

S K Bhattia, D R Hadden, D A Montgomery, J A Weaver.   

Abstract

In an initial trial of glibenclamide in the treatment of maturity onset diabetes mellitus 28 patients were treated for up to one year and no toxic effects or side-effects were encountered. The hypoglycaemic potency of this drug is such that 5 mg. of glibenclamide corresponds to about 1,500 mg. of tolbutamide and 375 mg. of chlorpropamide.

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Year:  1970        PMID: 5005518      PMCID: PMC1700204          DOI: 10.1136/bmj.2.5709.570

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  1 in total

1.  Oral hypoglycaemic agents.

Authors:  D R Hadden; J A Weaver
Journal:  Practitioner       Date:  1968-01
  1 in total
  5 in total

1.  Progress in oral therapy of diabetes mellitus with sulphonylureas of the second generation.

Authors:  S Raptis; E F Pfeiffer
Journal:  Acta Diabetol Lat       Date:  1972 Nov-Dec

2.  Hormonal and metabolic effects of chlorpropamide, glibenclamide and placebo in a cross-over study in diabetics not controlled by diet alone.

Authors:  P H Sönksen; C Lowy; J R Perkins; T E West
Journal:  Diabetologia       Date:  1981       Impact factor: 10.122

Review 3.  Glibenclamide: a review.

Authors: 
Journal:  Drugs       Date:  1971       Impact factor: 9.546

4.  Effects of metformin and glibenclamide on insulin receptors in fibroblasts and tumor cells in vitro.

Authors:  K G Mountjoy; G J Finlay; I M Holdaway
Journal:  J Endocrinol Invest       Date:  1987-12       Impact factor: 4.256

5.  Glibenclamide inhibits BK polyomavirus infection in kidney cells through CFTR blockade.

Authors:  Margarita-Maria Panou; Michelle Antoni; Ethan L Morgan; Eleni-Anna Loundras; Christopher W Wasson; Matthew Welberry-Smith; Jamel Mankouri; Andrew Macdonald
Journal:  Antiviral Res       Date:  2020-03-27       Impact factor: 5.970

  5 in total

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