| Literature DB >> 5000865 |
Abstract
A microbiological assay has been developed for chromomycin A(3), an antitumor antibiotic showing promise in human trials. The assay bacterium is a derived strain of Streptococcus faecalis resistant to methotrexate. Studies with mice revealed that relatively high concentrations of this antibiotic were maintained in the blood, kidneys, and liver of mice after a single-dose intraperitoneal injection of the drug.Entities:
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Year: 1971 PMID： 5000865 PMCID： PMC376303 DOI： 10.1128/am.22.3.300-302.1971
Source DB: PubMed Journal: Appl Microbiol ISSN： 0003-6919