Literature DB >> 4997172

The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos.

B Hogan, P R Gross.   

Abstract

Emetine is a potent inhibitor of protein synthesis in sea urchin embryos. At a concentration of the drug that rapidly inhibits protein synthesis in blastulae by 95%, uridine incorporation into RNA continues for more than 1 hr and presumptive histone messenger RNA is synthesized and transported into the cytoplasm where it is apparently associated with polyribosomes. Possible explanations of this result and its implications for the "informasome" theory of messenger transport in embryonic cells are discussed.

Entities:  

Mesh：

Substances：

Year:  1971        PMID： 4997172      PMCID： PMC2108483          DOI： 10.1083/jcb.49.3.692

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   10.539


  23 in total

1.  MESSENGER RNA DECAY AND PROTECTION.

Authors:  D P FAN; A HIGA; C LEVINTHAL
Journal:  J Mol Biol       Date:  1964-02       Impact factor: 5.469

2.  Structural basis for inhibition of protein synthesis by emetine and cycloheximide based on an analogy between ipecac alkaloids and glutarimide antibiotics.

Authors:  A P Grollman
Journal:  Proc Natl Acad Sci U S A       Date:  1966-12       Impact factor: 11.205

3.  The effect of HeLa cell cytoplasm on the rate of sedimentation of RNA.

Authors:  M Girard; D Baltimore
Journal:  Proc Natl Acad Sci U S A       Date:  1966-09       Impact factor: 11.205

4.  Inhibitors of protein biosynthesis. V. Effects of emetine on protein and nucleic acid biosynthesis in HeLa cells.

Authors:  A P Grollman
Journal:  J Biol Chem       Date:  1968-08-10       Impact factor: 5.157

5.  Synthesis of protein for DNA replication and cleavage events in the sand dollar embryo.

Authors:  C W Young; F J Hendler; D A Karnofsky
Journal:  Exp Cell Res       Date:  1969-11       Impact factor: 3.905

6.  Synthesis of ribosomal RNA during sea urchin development. II. Electrophoretic analysis of nuclear and cytoplasmic RNA's.

Authors:  G Giudice; V Mutolo
Journal:  Biochim Biophys Acta       Date:  1969-04-22

7.  Control of haemoglobin synthesis: rate of translation of the messenger RNA for the alpha and beta chains.

Authors:  T Hunt; T Hunter; A Munro
Journal:  J Mol Biol       Date:  1969-07-14       Impact factor: 5.469

8.  Identification in cleaving embryos of three RNA species serving as templates for the synthesis of nuclear proteins.

Authors:  L H Kedes; P R Gross
Journal:  Nature       Date:  1969-09-27       Impact factor: 49.962

9.  The mechanism of sodium fluoride and cycloheximide inhibition of hemoglobin biosynthesis in the cell-free reticulocyte system.

Authors:  S Y Lin; R D Mosteller; B Hardesty
Journal:  J Mol Biol       Date:  1966-10-28       Impact factor: 5.469

10.  The regulation of RNA synthesis and processing in the nucleolus during inhibition of protein synthesis.

Authors:  M Willems; M Penman; S Penman
Journal:  J Cell Biol       Date:  1969-04       Impact factor: 10.539
View more
  8 in total

1.  Dependence of timing of mitotic events on the rate of protein synthesis and DNA replication in sea urchin early cleavages.

Authors:  K Yamada
Journal:  Cell Prolif       Date:  1998 Oct-Dec       Impact factor: 6.831

2.  Stabilization of tubulin mRNA by inhibition of protein synthesis in sea urchin embryos.

Authors:  Z Y Gong; B P Brandhorst
Journal:  Mol Cell Biol       Date:  1988-08       Impact factor: 4.272

3.  Cell-free translation of maternal messenger RNA from sea urchin eggs.

Authors:  K W Gross; M Jacobs-Lorena; C Baglioni; P R Gross
Journal:  Proc Natl Acad Sci U S A       Date:  1973-09       Impact factor: 11.205

4.  Translational control in sea urchin eggs and embryos: initiation is rate limiting in blastula stage embryos.

Authors:  M B Hille; D C Hall; Z Yablonka-Reuveni; M V Danilchik; R T Moon
Journal:  Dev Biol       Date:  1981-08       Impact factor: 3.582

5.  Induction of a reductive pathway for deoxyribonucleotide synthesis during early embryogenesis of the sea urchin.

Authors:  J M Noronha; G H Sheys; J M Buchanan
Journal:  Proc Natl Acad Sci U S A       Date:  1972-08       Impact factor: 11.205

6.  Electrophoretic analysis of the stored histone pool in unfertilized sea urchin eggs: quantification and identification by antibody binding.

Authors:  J Salik; L Herlands; H P Hoffmann; D Poccia
Journal:  J Cell Biol       Date:  1981-08       Impact factor: 10.539

7.  Analysis of translation using polysome profiling.

Authors:  Héloïse Chassé; Sandrine Boulben; Vlad Costache; Patrick Cormier; Julia Morales
Journal:  Nucleic Acids Res       Date:  2017-02-17       Impact factor: 16.971

8.  Lipid species affect morphology of endoplasmic reticulum: a sea urchin oocyte model of reversible manipulation.

Authors:  Gabriela Ulloa; Fadi Hamati; Alexander Dick; Julie Fitzgerald; Judith Mantell; Paul Verkade; Lucy Collinson; Kenton Arkill; Banafshe Larijani; Dominic Poccia
Journal:  J Lipid Res       Date:  2019-09-23       Impact factor: 5.922
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.