Literature DB >> 4995297

Actinomycin D; renewed RNA synthesis after removal from mammalian cells.

A Schluederberg, R C Hendel, S Chavanich.   

Abstract

Suppressed RNA synthesis exceeded control rates 2 hours after removal of actinomycin from serial lines of green monkey kidney cells in exponentially dividing monolayer cultures. Enhanced synthesis was directly related to the dose of actinomycin, and release from inhibition was temperature dependent. A broad range of RNA sizes was made after removal of drug, but cytoplasmic and nucleolar sedimentation profiles were abnormal for at least 20 hours.

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Year:  1971        PMID： 4995297     DOI： 10.1126/science.172.3983.577

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

1.  Inhibiting eukaryotic transcription: Which compound to choose? How to evaluate its activity?

Authors:  Olivier Bensaude
Journal:  Transcription       Date:  2011-05

2.  Tentacle morphogenesis in hydra : I. The morphological effect of actinomycin D.

Authors:  Georgia E Lesh-Laurie; Leminh Hang
Journal:  Wilhelm Roux Arch Entwickl Mech Org       Date:  1972-12

Review 3.  Role of RNA and protein in memory storage: a review.

Authors:  L L Uphouse; J W MacInnes; K Schlesinger
Journal:  Behav Genet       Date:  1974-03       Impact factor: 2.805

4.  Japanese encephalitis virus replication: a procedure for the selective isolation and characterization of viral RNA species.

Authors:  E Zebovitz; J K Leong; S C Doughty
Journal:  Arch Gesamte Virusforsch       Date:  1972

5.  In vivo degradation of RNA polymerase II largest subunit triggered by alpha-amanitin.

Authors:  V T Nguyen; F Giannoni; M F Dubois; S J Seo; M Vigneron; C Kédinger; O Bensaude
Journal:  Nucleic Acids Res       Date:  1996-08-01       Impact factor: 16.971

6.  Resistance of African green monkey kidney cell lines to actinomycin D: drug uptake in 37 RC cells after persistent inhibition of transcription.

Authors:  A Benedetto; A Cassone; C Delfini
Journal:  Antimicrob Agents Chemother       Date:  1979-02       Impact factor: 5.191

7.  Enhancement and suppression by actinomycin D of a Vero cell nontransmissible measles infection.

Authors:  S H Winston; R Rustigian
Journal:  Infect Immun       Date:  1979-06       Impact factor: 3.441

8.  Study on the reinitiation of transcription in 37 RC cells after actinomycin D inhibition. Spectrum of major RNA species resynthesized after maximal suppression by the drug.

Authors:  A Benedetto; C Delfini; G Carloni; W Djaczenko
Journal:  J Cell Biol       Date:  1975-12       Impact factor: 10.539

9.  Regulation of mRNA export by the PI3 kinase/AKT signal transduction pathway.

Authors:  Alexandre Jose Christino Quaresma; Rachel Sievert; Jeffrey A Nickerson
Journal:  Mol Biol Cell       Date:  2013-02-20       Impact factor: 4.138

10.  37RC cells rapidly recover their RNA synthesis after inhibition with high doses of actinomycin D.

Authors:  A Benedetto; W Djaczenko
Journal:  J Cell Biol       Date:  1972-01       Impact factor: 10.539
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