Literature DB >> 499410

Changes of X-prolyl dipeptidyl-aminopeptidase activity in developing rat brain.

T Kato, T Hama, T Nagatsu, H Kuzuya, S Sakakibara.   

Abstract

We found X-prolyl dipeptidyl-aminopeptidase activity in rat brain and examined the developmental changes at various ages. The total enzyme activity per brain increased until 4 weeks of age, and then decreased during maturation. Specific activity in young rat brain was higher than that in adult rat brain. The properties of the brain enzyme were different from those of pituitary and other tissues.

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Year:  1979        PMID： 499410     DOI： 10.1007/bf01963989

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  Changes in proteolytic enzymes and proteins during maturation of the brain.

Authors:  N Marks; F Stern; A Lajtha
Journal:  Brain Res       Date:  1975-03-21       Impact factor: 3.252

2.  Prolidase activity in rat brain; developmental, regional and subcellular distribution.

Authors:  K S Hui; A Lajtha
Journal:  Brain Res       Date:  1978-09-15       Impact factor: 3.252

3.  New chromogenic substrates for X-prolyl dipeptidyl-aminopeptidase.

Authors:  T Nagatsu; M Hino; H Fuyamada; T Hayakawa; S Sakakibara
Journal:  Anal Biochem       Date:  1976-08       Impact factor: 3.365

4.  Stimulatory effects of substance P on neurite extension and cyclic AMP levels in cultured neuroblastoma cells.

Authors:  S Narumi; Y Maki
Journal:  J Neurochem       Date:  1978-06       Impact factor: 5.372

5.  Fluorescence assay of x-prolyl dipeptidyl-aminopeptidase activity with a new fluorogenic substrate.

Authors:  T Kato; T Nagatsu; T Kimura; S Sakakibara
Journal:  Biochem Med       Date:  1978-06

6.  Purification and properties of glycylprolyl -naphthylamidase in human submaxillary gland.

Authors:  H Oya; I Nagatsu; T Nagatsu
Journal:  Biochim Biophys Acta       Date:  1972-02-28

7.  Hydrolysis of amino acid beta-naphthylamides by aminopeptidases in human parotid salva and human serum.

Authors:  I Nagatsu; T Nagatsu; T Yamamoto
Journal:  Experientia       Date:  1968-04-15

8.  A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-beta-naphthylamide.

Authors:  V K Hopsu-Havu; G G Glenner
Journal:  Histochemie       Date:  1966

9.  Successive cleavage of N-terminal Arg1--Pro2 and Lys3-Pro4 from substance P but no release of Arg1-Pro2 from bradykinin, by X-Pro dipeptidyl-aminopeptidase.

Authors:  T Kato; T Nagatsu; K Fukasawa; M Harada; I Nagatsu; S Sakakibara
Journal:  Biochim Biophys Acta       Date:  1978-08-07

10.  Studies on substrate specificity of X-prolyl dipeptidyl-aminopeptidase during new chromogenic substrates, X-Y-p-nitroanilides.

Authors:  T Kato; T Nagatsu; T Kimura; S Sakakibara
Journal:  Experientia       Date:  1978-03-15
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  3 in total

1.  Dipeptidyl aminopeptidase in neonatal rat brain regions.

Authors:  K Imai; T Kato
Journal:  Experientia       Date:  1984-03-15

2.  Comparative immunohistochemistry and histochemistry of dipeptidyl peptidase IV in rat organs during development.

Authors:  S Hartel-Schenk; R Gossrau; W Reutter
Journal:  Histochem J       Date:  1990-10

3.  Mass spectrometry-assisted confirmation of the inability of dipeptidyl peptidase-4 to cleave goldfish peptide YY(1-36) and the lack of anorexigenic effects of peptide YY(3-36) in goldfish (Carassius auratus).

Authors:  R Gonzalez; S Unniappan
Journal:  Fish Physiol Biochem       Date:  2015-12-16       Impact factor: 2.794
  3 in total

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