Literature DB >> 499239

Accumulation of radioiodinated tyrosine derivatives in the adrenal medulla and in melanomas.

G Kloss, M Leven.   

Abstract

Because tyrosine and dopa can be regarded as precursors of adrenomedullary hormones and melanin, radioiodinated derivatives of these compounds were tested for their accumulation in the adrenal medulla and in melanomas of various animal species. The highest level of accumulation in the adrenal medulla was attained in mice and rats with iodinated beta-hydroxy-alpha-methyltyramine, and in melanomas of mice with iodinated alpha-methyltyrosine. The results could not be reproduced to the same extent in other species.

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Year:  1979        PMID: 499239     DOI: 10.1007/bf00620482

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN: 0340-6997


  15 in total

1.  [Studies on controlled radiotherapy of melanoma and on the chromaffin system by selective H-3 incorporation after administration of H-3-labelled DOPA].

Authors:  K HEMPEL; M DEIMEL
Journal:  Strahlentherapie       Date:  1963-05

2.  Radioactivity from labeled precursors of melanin in mice and hamsters with melanomas.

Authors:  D A Meier; W H Beierwaltes; R E Counsell
Journal:  Cancer Res       Date:  1967-08       Impact factor: 12.701

3.  Synthesis and preliminary evaluation in animals of carrier-free 11C-1-dopamine hydrochloride: X.

Authors:  J S Fowler; A N Ansari; H L Atkins; P R Bradley-Moore; R R MacGregor; A P Wolf
Journal:  J Nucl Med       Date:  1973-11       Impact factor: 10.057

4.  Labeled dopamine concentration in pheochromocytomas.

Authors:  B G Anderson; W H Beierwaltes; T S Harrison; A N Ansari; A A Buswink; R D Ice
Journal:  J Nucl Med       Date:  1973-11       Impact factor: 10.057

5.  Autoradiographic studies on the role of adrenaline in stress by using H3 adrenaline.

Authors:  G C Prasad; M Z Siddigui; K N Udupa
Journal:  Am J Roentgenol Radium Ther Nucl Med       Date:  1973-08

6.  [Animal whole-body autoradiography, a method of drug research].

Authors:  K Patzschke
Journal:  Munch Med Wochenschr       Date:  1968-09-06

7.  Visualizing human malignant melanoma and metastases. Use of chloroquine analog tagged with iodine 125.

Authors:  W H Beierwaltes; L M Lieberman; V M Varma; R E Counsell
Journal:  JAMA       Date:  1968-09-30       Impact factor: 56.272

8.  Organic radiopharmaceuticals labeled with short-lived nuclides. 3. 18F-labeled phenylalanines.

Authors:  R M Hoyte; S S Lin; D R Christman; H L Atkins; W Hauser; A P Wolf
Journal:  J Nucl Med       Date:  1971-06       Impact factor: 10.057

9.  The concentration of radioactivity from labeled epinephrine and its precursors in the dog adrenal medulla.

Authors:  J O Morales; W H Beierwaltes; R E Counsell; D H Meier
Journal:  J Nucl Med       Date:  1967-11       Impact factor: 10.057

10.  Concentration of dopamine analogs in the adrenal medulla.

Authors:  R D Ice; D M Wieland; W H Beirwaltes; R G Lawton; M J Redmond
Journal:  J Nucl Med       Date:  1975-12       Impact factor: 10.057

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  10 in total

1.  The history of 123-iodo-methyl tyrosine.

Authors:  H J Biersack
Journal:  Eur J Nucl Med       Date:  2001-03

Review 2.  Tracers for metabolic imaging of brain and heart. Radiochemistry and radiopharmacology.

Authors:  G Stöcklin
Journal:  Eur J Nucl Med       Date:  1992

3.  [Noncontact detection of intraocular lesions by means of a gamma scintillation camera].

Authors:  H Bockslaff; D Dausch; H Bornemann; L Stöppler; H Hundeshagen
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1979-09

4.  N-(2-diethylaminoethyl)-4-[123I]iodobenzamide as a tracer for the detection of malignant melanoma: simple synthesis, improved labelling technique and first clinical results.

Authors:  W Brandau; B Kirchner; P Bartenstein; J Sciuk; D Kamanabrou; O Schober
Journal:  Eur J Nucl Med       Date:  1993-03

5.  Noncontact detection of experimental amelanotic ocular melanoma with L-3-123I-iodo-alpha-methyltyrosine.

Authors:  H Bockslaff; M Spitznas; I Hahn; G Kloster
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1981

6.  Noncontact detection of ocular melanoma with L-3-123I-iodo-alpha-methyltyrosine: first clinical results.

Authors:  H Bockslaff; G Kloster; D Dausch; K Schad; H Hundeshagen
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1982       Impact factor: 3.117

7.  [125I] radioiodinated metaraminol: a new platelet-specific labeling agent.

Authors:  Y Ohmomo; A Yokoyama; K Kawai; Y Arano; K Horiuchi; C Tanaka; H Saji; K Torizuka
Journal:  Eur J Nucl Med       Date:  1985

8.  Melanoma affine radiopharmaceuticals I. A comparative study of 131I-labeled quinoline and tyrosine derivatives.

Authors:  B Bubeck; M Eisenhut; U Heimke; K zum Winkel
Journal:  Eur J Nucl Med       Date:  1981

9.  Canine SPECT studies for cerebral amino acid transport by means of 123I-3-iodo-alpha-methyl-L-tyrosine and preliminary kinetic analysis.

Authors:  K Kawai; Y Fujibayashi; Y Yonekura; K Tanaka; H Saji; J Konishi; A Kubodera; A Yokoyama
Journal:  Ann Nucl Med       Date:  1995-02       Impact factor: 2.668

10.  Reconstruction of Tissue-Specific Metabolic Networks Using CORDA.

Authors:  André Schultz; Amina A Qutub
Journal:  PLoS Comput Biol       Date:  2016-03-04       Impact factor: 4.475

  10 in total

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