Literature DB >> 4990766

Mode of action of 2-nitro-1-butyl pyridinium sulfate.

R Seale, D J Weber.   

Abstract

Ten micrograms of 2-nitro-1-butyl pyridinium sulfate (NBPS) per milliliter inhibited the growth of Bacillus subtilis by blocking thymidylate synthetase. The inhibition could be reversed by the addition of thymine or cytosine.

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Year:  1970        PMID: 4990766      PMCID: PMC248247          DOI: 10.1128/jb.104.1.590-593.1970

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  13 in total

1.  Purification and properties of the formate-activating enzyme from erythrocytes.

Authors:  J R BERTINO; B SIMMONS; D M DONOHUE
Journal:  J Biol Chem       Date:  1962-04       Impact factor: 5.157

2.  Ribonucleic acid synthesis and thymineless death.

Authors:  J GALLANT; S R SUSKIND
Journal:  Biochim Biophys Acta       Date:  1962-05-14

3.  Enzymatic synthesis of deoxyribonucleic acid. I. Preparation of substrates and partial purification of an enzyme from Escherichia coli.

Authors:  I R LEHMAN; M J BESSMAN; E S SIMMS; A KORNBERG
Journal:  J Biol Chem       Date:  1958-07       Impact factor: 5.157

4.  Folic acid antagonists.

Authors:  H G PETERING
Journal:  Physiol Rev       Date:  1952-04       Impact factor: 37.312

5.  Thymidylate synthesis and aminopterin resistance in Bacillus subtilis.

Authors:  M C Wilson; J L Farmer; F Rothman
Journal:  J Bacteriol       Date:  1966-07       Impact factor: 3.490

6.  Nonconservative DNA replication in bacteria after thymine starvation.

Authors:  C Pauling; P Hanawalt
Journal:  Proc Natl Acad Sci U S A       Date:  1965-12       Impact factor: 11.205

7.  The thymineless death and deoxyribosideless death in Lactobacillus acidophilus R-26.

Authors:  J Reich; J Soska
Journal:  Biochem Biophys Res Commun       Date:  1967-10-11       Impact factor: 3.575

8.  Thymineless death in Escherichia coli 15T- and recombinants of 15T- and Escherichia coli K-12.

Authors:  G Medoff; S Overholt
Journal:  J Bacteriol       Date:  1970-04       Impact factor: 3.490

9.  Thymineless death in Escherichia coli: deoxyribonucleic acid replication and the immune state.

Authors:  D J Cummings; A R Kusy
Journal:  J Bacteriol       Date:  1970-04       Impact factor: 3.490

10.  Thymineless death in Escherichia coli: strain specificity.

Authors:  D J Cummings; L Mondale
Journal:  J Bacteriol       Date:  1967-06       Impact factor: 3.490

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