Literature DB >> 4988896

Plasmodium falciparum in owl monkeys: drug resistance and chloroquine binding capacity.

C D Fitch.   

Abstract

Erythrocytes infected with chloroquine-sensitive Plasmodium falciparum bind chloroquine with an apparent intrinsic association constant of 1.5 x 10(7) liters per mole. Such high-affinity binding of chloroquine is absent or deficient in uninfected erythrocytes and in erythrocytes infected with chloroquine-resistant Plasmodium falciparum.

Entities:  

Mesh：

Substances：

Year:  1970        PMID： 4988896     DOI： 10.1126/science.169.3942.289

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  39 in total

1.  Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.

Authors:  D A Fidock; T Nomura; A K Talley; R A Cooper; S M Dzekunov; M T Ferdig; L M Ursos; A B Sidhu; B Naudé; K W Deitsch; X Z Su; J C Wootton; P D Roepe; T E Wellems
Journal:  Mol Cell       Date:  2000-10       Impact factor: 17.970

2.  Degrees of chloroquine resistance in Plasmodium - is the redox system involved?

Authors:  Adele M Lehane; Christopher A McDevitt; Kiaran Kirk; David A Fidock
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2012-12-01       Impact factor: 4.077

3.  Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum.

Authors:  Cecilia P Sanchez; Petra Rohrbach; Jeremy E McLean; David A Fidock; Wilfred D Stein; Michael Lanzer
Journal:  Mol Microbiol       Date:  2007-04       Impact factor: 3.501

4.  Simple Molecular Methods for Early Detection of Chloroquine Drug Resistance in Plasmodium vivax and Plasmodium falciparum.

Authors:  Gurjeet Singh; Raksha Singh; Anant Dattatraya Urhehar
Journal:  J Clin Diagn Res       Date:  2016-07-01

5.  Use of radioactive ethanolamine incorporation into phospholipids to assess in vitro antimalarial activity by the semiautomated microdilution technique.

Authors:  N Elabbadi; M L Ancelin; H J Vial
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

6.  Chloroquine uptake by Plasmodium falciparum-infected human erythrocytes during in vitro culture and its relationship to chloroquine resistance.

Authors:  F Verdier; J Le Bras; F Clavier; I Hatin; M C Blayo
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

Review 7.  Clinical pharmacokinetics of antimalarial drugs.

Authors:  N J White
Journal:  Clin Pharmacokinet       Date:  1985 May-Jun       Impact factor: 6.447

8.  Lysis of Plasmodium falciparum by ferriprotoporphyrin IX and a chloroquine-ferriprotoporphyrin IX complex.

Authors:  C D Fitch; R Chevli; H S Banyal; G Phillips; M A Pfaller; D J Krogstad
Journal:  Antimicrob Agents Chemother       Date:  1982-05       Impact factor: 5.191

9.  Chloroquine resistance-conferring mutations in pfcrt give rise to a chloroquine-associated H+ leak from the malaria parasite's digestive vacuole.

Authors:  Adele M Lehane; Kiaran Kirk
Journal:  Antimicrob Agents Chemother       Date:  2008-10-13       Impact factor: 5.191

10.  Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.

Authors:  David J Johnson; David A Fidock; Mathirut Mungthin; Viswanathan Lakshmanan; Amar Bir Singh Sidhu; Patrick G Bray; Stephen A Ward
Journal:  Mol Cell       Date:  2004-09-24       Impact factor: 17.970
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.