Literature DB >> 4987310

Radiation sensitivity of Haemophilus influenzae: a composite response.

B J Barnhart, S H Cox.   

Abstract

The survival of ultraviolet (UV)-irradiated cultures of Haemophilus influenzae Rd is determined by at least two responses: (i) excision-repair ability and (ii) UV-induced cell lysis. An UV-resistant mutant, BC200, has the same capabilities as the wild type, Rd, for excising dimers but does not exhibit lysis. Lytic response is dose-dependent. Relative to the wild type, a lower dose of UV causes lysis of a UV-sensitive mutant, BC100, which is incapable of excising thymine dimers. A lytic protein is present in cultures undergoing lysis. Synthesis of this protein is initiated 45 to 60 min after irradiation. Lysis appears to be due to derepression of a defective prophage which codes for an endolysin-like lytic enzyme.

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Year:  1970        PMID： 4987310      PMCID： PMC248031          DOI： 10.1128/jb.103.1.9-15.1970

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  16 in total

1.  Studies on the radiation inactivation of microorganisms. V. Deoxyribonucleic acid metabolism in ultraviolet-irradiated Haemophilus influenzae.

Authors:  J H STUY
Journal:  J Bacteriol       Date:  1959-07       Impact factor: 3.490

2.  INFECTION OF TRANSFORMABLE CELLS OF HAEMOPHILUS INFLUENZAE BY BACTERIOPHAGE AND BACTERIOPHAGE DNA.

Authors:  W HARM; C S RUPERT
Journal:  Z Vererbungsl       Date:  1963-12-30

3.  THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM.

Authors:  R B SETLOW; W L CARRIER
Journal:  Proc Natl Acad Sci U S A       Date:  1964-02       Impact factor: 11.205

4.  The mechanism of lysis by phage studied with defective lysogenic bacteria.

Authors:  F JACOB; C R FUERST
Journal:  J Gen Microbiol       Date:  1958-04

5.  [Induction of the production of bacteriophages in lysogenic bacteria].

Authors:  A LWOFF; L SIMINOVITCH; N KJELDGAARD
Journal:  Ann Inst Pasteur (Paris)       Date:  1950-12

6.  "Excision repair" and dose-modification: questions raised by radiobiological experiments with acriflavine.

Authors:  T Alper; B Hodgkins
Journal:  Mutat Res       Date:  1969 Jul-Aug       Impact factor: 2.433

7.  Repair of DNA in Haemophilus influenzae. II. Excision, repair of single-strand breaks, defects in transformation, and host cell modification in UV-sensitive mutants.

Authors:  J K Setlow; M L Randolph; M E Boling; A Mattingly; G Price; M P Gordon
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1968

8.  Incomplete bacteriophage-like particles in ultraviolet-irradiated haemophilus.

Authors:  I Stachura; F W Mckinley; G Leidy; H E Alexander
Journal:  J Bacteriol       Date:  1969-05       Impact factor: 3.490

9.  Repair of deoxyribonucleic acid in Haemophilus influenzae. I. X-ray sensitivity of ultraviolet-sensitive mutants and their behavior as hosts to ultraviolet-irradiated bacteriophage and transforming deoxyribonucleic acid.

Authors:  J K Setlow; D C Brown; M E Boling; A Mattingly; M P Gordon
Journal:  J Bacteriol       Date:  1968-02       Impact factor: 3.490

10.  Induction of streptomycin resistance in sensitive Hemophilus influenzae by extracts containing desoxyribonucleic acid from resistant Hemophilus influenzae.

Authors:  H E ALEXANDER; G LEIDY
Journal:  J Exp Med       Date:  1953-01       Impact factor: 14.307
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  8 in total

1.  Prophage induction and inactivation by UV light.

Authors:  B J Barnhart; S H Cox; J H Jett
Journal:  J Virol       Date:  1976-06       Impact factor: 5.103

2.  Restriction enzymes do not play a significant role in Haemophilus homospecific or heterospecific transformation.

Authors:  J H Stuy
Journal:  J Bacteriol       Date:  1976-10       Impact factor: 3.490

3.  Heat sensitivity of Haemophilus influenzae containing defective prophage.

Authors:  J K Setlow
Journal:  J Bacteriol       Date:  1977-12       Impact factor: 3.490

4.  Bacteriocin factors responsible for UV-sensitivity and susceptibility to post-irradiation breakdown of DNA.

Authors:  T Alper; A J Forage; L Afzal
Journal:  Mol Gen Genet       Date:  1972

5.  Repair of single-strand deoxyribonucleic acid breaks in ultraviolet light-irradiated Haemophilus influenzae.

Authors:  G J Kantor; B J Barnhart
Journal:  J Bacteriol       Date:  1973-03       Impact factor: 3.490

6.  Unauthorized horizontal spread in the laboratory environment: the tactics of Lula, a temperate lambdoid bacteriophage of Escherichia coli.

Authors:  Ella Rotman; Luciana Amado; Andrei Kuzminov
Journal:  PLoS One       Date:  2010-06-14       Impact factor: 3.240

7.  Inducible repair system in Haemophilus influenzae unaccompanied by mutation.

Authors:  N K Notani; J K Setlow
Journal:  J Bacteriol       Date:  1980-07       Impact factor: 3.490

8.  Accumulation of incomplete particles after uv-light induction of Haemophilus influenzae lysogenic for bacteriophage HP1C1.

Authors:  R T Okinaka; B J Barnhart
Journal:  J Virol       Date:  1974-12       Impact factor: 5.103
  8 in total

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