Literature DB >> 4986716

Selective destruction of target cells by diphtheria toxin conjugated to antibody directed against antigens on the cells.

F L Moolten, S R Cooperband.   

Abstract

Monkey-kidney cells bearing new surface antigens induced by infection with mumps virus were lysed selectively by diphtheria toxin conjugated to antibody against mumps antigens.

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Year:  1970        PMID： 4986716     DOI： 10.1126/science.169.3940.68

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  33 in total

Review 1.  Diphtheria toxin: mode of action and structure.

Authors:  R J Collier
Journal:  Bacteriol Rev       Date:  1975-03

Review 2.  Immunotoxins for targeted cancer therapy.

Authors:  Robert J Kreitman
Journal:  AAPS J       Date:  2006-08-18       Impact factor: 4.009

3.  Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion.

Authors:  M Kathryn Brewer; Annette Uittenbogaard; Grant L Austin; Dyann M Segvich; Anna DePaoli-Roach; Peter J Roach; John J McCarthy; Zoe R Simmons; Jason A Brandon; Zhengqiu Zhou; Jill Zeller; Lyndsay E A Young; Ramon C Sun; James R Pauly; Nadine M Aziz; Bradley L Hodges; Tracy R McKnight; Dustin D Armstrong; Matthew S Gentry
Journal:  Cell Metab       Date:  2019-07-25       Impact factor: 27.287

4.  In vivo and in vitro effects of tumour specific antibodies with chlorambucil.

Authors:  D A Davies; G J O'Neill
Journal:  Br J Cancer Suppl       Date:  1973-08

5.  Cloning and expression in Escherichia coli of three fragments of diphtheria toxin truncated within fragment B.

Authors:  W R Bishai; A Miyanohara; J R Murphy
Journal:  J Bacteriol       Date:  1987-04       Impact factor: 3.490

Review 6.  Next generation antibody drugs: pursuit of the 'high-hanging fruit'.

Authors:  Paul J Carter; Greg A Lazar
Journal:  Nat Rev Drug Discov       Date:  2017-12-01       Impact factor: 84.694

7.  Enzymatic activation and trapping of luminol-substituted peptides and proteins. A possible means of amplifying the cytotoxicity of anti-tumor antibodies.

Authors:  C W Parker; R D Aach; G W Philpott
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

8.  The effect of abrin, anti-lymphocyte globulin and their conjugates on the immune response of mice to sheep red blood cells.

Authors:  D C Edwards; A Smith; W C Ross; A J Cumber; P E Thorpe; A J Davies
Journal:  Experientia       Date:  1981-03-15

Review 9.  Immunotherapeutic strategies to target prognostic and predictive markers of cancer.

Authors:  Michael S Magee; Adam E Snook; Glen P Marszalowicz; Scott A Waldman
Journal:  Biomark Med       Date:  2013-02       Impact factor: 2.851

10.  Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin.

Authors:  R J Youle; D M Neville
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205
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