Literature DB >> 498102

Correlation between glucocorticoid receptor and cytolytic response of murine lymphoid cell lines.

S Bourgeois, R F Newby.   

Abstract

By fusion between murine thymoma lines which are either homozygous (r+/r+ or r-/r-) or hemizygous (r+/r-) for the glucocorticoid receptor structural gene r, hybrid clones have been obtained which carry one, two three, or four copies of the r+ allele. These hybrids contain different amounts of normal glucocorticoid receptor as the result of a r+ gene dosage effect. Measurements of the cytolytic response of these hybrids to dexamethasone indicate a tight correlation between receptor content and sensitivity.

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Year:  1979        PMID： 498102

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  18 in total

1.  Effects of dexamethasone on the growth of cultured rabbit articular chondrocytes:relation with the nuclear glucocorticoid-receptor complex.

Authors:  B Hainque; J Dominice; P Jaffray; X Ronot; M Adolphe
Journal:  Ann Rheum Dis       Date:  1987-02       Impact factor: 19.103

2.  Number of glucocorticoid receptors in lymphocytes and their sensitivity to hormone action.

Authors:  I E Petrichenko; N A Gratsianski; O I Aleshin; N V Chepurnenko; N V Perova
Journal:  Experientia       Date:  1989-12-01

3.  Corticotropin-releasing hormone, proopiomelanocortin, and glucocorticoid receptor gene expression in adrenocorticotropin-producing tumors in vitro.

Authors:  T Suda; F Tozawa; I Dobashi; N Horiba; N Ohmori; M Yamakado; M Yamada; H Demura
Journal:  J Clin Invest       Date:  1993-12       Impact factor: 14.808

4.  Down-regulation of glucocorticoid receptors in mouse lymphoma cell variants.

Authors:  M Danielsen; M R Stallcup
Journal:  Mol Cell Biol       Date:  1984-03       Impact factor: 4.272

Review 5.  Understanding how long-acting β2 -adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids in asthma - an update.

Authors:  Robert Newton; Mark A Giembycz
Journal:  Br J Pharmacol       Date:  2016-11-09       Impact factor: 8.739

6.  Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone.

Authors:  S Okret; L Poellinger; Y Dong; J A Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

7.  Gamma interferon down-regulates glucocorticoid receptor expression and attenuates hormone action in a human osteosarcoma cell line.

Authors:  L N Song
Journal:  Endocrine       Date:  1995-10       Impact factor: 3.633

8.  Attenuation of glucocorticoid receptor levels by the H-ras oncogene.

Authors:  V R Martins; M M Brentani; P R Housley
Journal:  Endocrine       Date:  1995-04       Impact factor: 3.633

9.  Glucocorticoid receptor level, terminal deoxynucleotidyl transferase activity and initial responsiveness to prednisone and vincristine in leukemia.

Authors:  A D Ho; S Stojakowits; H Pralle; M Dörner; W Hunstein
Journal:  Klin Wochenschr       Date:  1983-05-02

10.  Ligand-induced repression of the glucocorticoid receptor gene is mediated by an NCoR1 repression complex formed by long-range chromatin interactions with intragenic glucocorticoid response elements.

Authors:  Sivapriya Ramamoorthy; John A Cidlowski
Journal:  Mol Cell Biol       Date:  2013-02-19       Impact factor: 4.272
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