Literature DB >> 497816

Antiserum induced myelination inhibition in vitro without complement.

S H Dorfman, J M Fry, D H Silberberg.   

Abstract

Exposure of neonatal rat cerebellum cultures to antiserum to whole spinal cord or galactocerebroside inhibited myelin formation regardless of whether guinea pig serum was added fresh or after heating to 56 degrees C for 1 h in order to achieve complete removal of hemolytic complement activity. Myelination followed removal of antisera from the culture media. This suggests that the inhibition of primary myelination by anti-CNS tissue antiserum occurs through some mechanism other than as the result of a cytotoxic reaction against oligodendrocytes mediated via the complement system.

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Year:  1979        PMID: 497816     DOI: 10.1016/0006-8993(79)90921-1

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  10 in total

1.  Suppression of the onset of myelination extends the permissive period for the functional repair of embryonic spinal cord.

Authors:  H S Keirstead; S J Hasan; G D Muir; J D Steeves
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

2.  Anti-reovirus receptor antibody accelerates expression of the optic nerve oligodendrocyte developmental program.

Authors:  J A Cohen; W V Williams; H M Geller; M I Greene
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-15       Impact factor: 11.205

3.  Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside.

Authors:  B Ranscht; P A Clapshaw; J Price; M Noble; W Seifert
Journal:  Proc Natl Acad Sci U S A       Date:  1982-04       Impact factor: 11.205

4.  Negative regulation of oligodendrocyte differentiation by galactosphingolipids.

Authors:  R Bansal; S Winkler; S Bheddah
Journal:  J Neurosci       Date:  1999-09-15       Impact factor: 6.167

5.  Shared antigenic determinants between brain and thymus-derived lymphocytes in dogs.

Authors:  S Krakowka; A L Wallace; A Koestner
Journal:  Acta Neuropathol       Date:  1981       Impact factor: 17.088

Review 6.  Abnormal serum factors in Guillain-Barré syndrome.

Authors:  R P Lisak; M J Brown; A J Summer
Journal:  Ital J Neurol Sci       Date:  1983-09

7.  Glycolipids and transmembrane signaling: antibodies to galactocerebroside cause an influx of calcium in oligodendrocytes.

Authors:  C A Dyer; J A Benjamins
Journal:  J Cell Biol       Date:  1990-08       Impact factor: 10.539

Review 8.  Central nervous system myelin: structure, function, and pathology.

Authors:  C M Deber; S J Reynolds
Journal:  Clin Biochem       Date:  1991-04       Impact factor: 3.281

9.  Transcriptional regulation of the human UDP-galactose:ceramide galactosyltransferase (hCGT) gene expression: functional role of GC-box and CRE.

Authors:  Tewin Tencomnao; Dmitri Kapitonov; Erhard Bieberich; Robert K Yu
Journal:  Glycoconj J       Date:  2004       Impact factor: 3.009

10.  Acute Autonomic Symptoms with Anti-myelin-associated Glycoprotein Neuropathy as a Presentation of Small B Cell Lymphoma: A Case Report and Literature Review.

Authors:  Muhammad Umair Jahngir; Raghav Govindarajan
Journal:  Cureus       Date:  2018-08-06
  10 in total

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