Literature DB >> 497534

The inhibitory material in extracts from the bovine retractor penis muscle is not an adenine nucleotide.

A Bowman, J S Gillespie, W Martin.   

Abstract

Methods are described for the removal of adenosine or purine nucleotides from extracts of bovine retractor penis muscle (BRP). These methods did not interfere with the biological test preparations. Removal of adenosine and purine nucleotides by these methods did not modify the inhibitory action of the extract on the BRP. The effect of the extract on the BRP resembles that of inhibitory nerve stimulation. If the inhibitory substance present in the extract is the inhibitory transmitter, then the results indicate that, in this tissue, the transmitter is neither adenosine nor a purine nucleotide.

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Year:  1979        PMID: 497534      PMCID: PMC2043974          DOI: 10.1111/j.1476-5381.1979.tb08683.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  6 in total

1.  Extraction from ox retractor penis of an inhibitory substance which mimics its atropine-resistant neurogenic relaxation.

Authors:  N Ambache; S W Killick; M Aboo Aar
Journal:  Br J Pharmacol       Date:  1975-07       Impact factor: 8.739

Review 2.  Purinergic nerves.

Authors:  G Burnstock
Journal:  Pharmacol Rev       Date:  1972-09       Impact factor: 25.468

3.  Contraction and relaxation of the retractor penis muscle and the penile artery of the bull.

Authors:  E Klinge; N O Sjöstrand
Journal:  Acta Physiol Scand Suppl       Date:  1974

4.  Evidence for purinergic innervation of the anococcygeus muscle.

Authors:  G Burnstock; T Cocks; R Crowe
Journal:  Br J Pharmacol       Date:  1978-09       Impact factor: 8.739

5.  A smooth muscle inhibitory material extracted from the bovine retractor penis and rat anococcygeus muscles [proceedings].

Authors:  J S Gillespie; W Martin
Journal:  J Physiol       Date:  1978-07       Impact factor: 5.182

6.  The rat anococcygeus muscle and its response to nerve stimulation and to some drugs.

Authors:  J S Gillespie
Journal:  Br J Pharmacol       Date:  1972-07       Impact factor: 8.739

  6 in total
  13 in total

1.  The mechanisms by which haemoglobin inhibits the relaxation of rabbit aorta induced by nitrovasodilators, nitric oxide, or bovine retractor penis inhibitory factor.

Authors:  W Martin; J A Smith; D G White
Journal:  Br J Pharmacol       Date:  1986-11       Impact factor: 8.739

2.  Endothelium-derived relaxing factor inhibits in vitro platelet aggregation.

Authors:  B Furlong; A H Henderson; M J Lewis; J A Smith
Journal:  Br J Pharmacol       Date:  1987-04       Impact factor: 8.739

3.  The effect of an inhibitory factor from the bovine retractor penis on the gastro-intestinal tract and gall bladder of the guinea-pig.

Authors:  A W Crossley; J S Gillespie
Journal:  Br J Pharmacol       Date:  1983-01       Impact factor: 8.739

4.  A smooth muscle inhibitory material from the bovine retractor penis and rat anococcygeus muscles.

Authors:  J S Gillespie; W Martin
Journal:  J Physiol       Date:  1980-12       Impact factor: 5.182

5.  Block of some non-adrenergic inhibitory responses of smooth muscle by a substance from haemolysed erythrocytes.

Authors:  A Bowman; J S Gillespie
Journal:  J Physiol       Date:  1982-07       Impact factor: 5.182

6.  Some physical and chemical properties of the smooth muscle inhibitory factor in extracts of the bovine retractor penis muscle.

Authors:  J S Gillespie; J C Hunter; W Martin
Journal:  J Physiol       Date:  1981-06       Impact factor: 5.182

7.  Mechanisms underlying electrical and mechanical responses of the bovine retractor penis to inhibitory nerve stimulation and to an inhibitory extract.

Authors:  N G Byrne; T C Muir
Journal:  Br J Pharmacol       Date:  1985-05       Impact factor: 8.739

8.  Actions on the cardiovascular system of an inhibitory material extracted from the bovine retractor penis.

Authors:  A Bowman; J S Gillespie; W Martin
Journal:  Br J Pharmacol       Date:  1981-02       Impact factor: 8.739

9.  A comparison of the action of the endothelium-derived relaxant factor and the inhibitory factor from the bovine retractor penis on rabbit aortic smooth muscle.

Authors:  A Bowman; J S Gillespie; P Soares-da-Silva
Journal:  Br J Pharmacol       Date:  1986-01       Impact factor: 8.739

10.  Cyclic GMP mediates neurogenic relaxation in the bovine retractor penis muscle.

Authors:  A Bowman; A H Drummond
Journal:  Br J Pharmacol       Date:  1984-04       Impact factor: 8.739

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