Literature DB >> 4972298

Factor 8 and antibody levels in plasma fractions prepated by cryoprecipitation.

A Pollock.   

Abstract

Most of the antibody activity of plasma was found to remain in the supernatant fraction following the preparation of factor-VIII-rich cryoprecipitates. The low level of antibody remaining in these cryoprecipitates indicated that they could safely be used as a source of factor VIII for replacement therapy. Washing the cryoprecipitates farther reduced their antibody titres without materially affecting their factor VIII content.

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Year:  1968        PMID: 4972298      PMCID: PMC473878          DOI: 10.1136/jcp.21.5.635

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  9 in total

1.  PREVENTION OF RH-HAEMOLYTIC DISEASE: A THIRD REPORT.

Authors:  J C WOODROW; C A CLARKE; W T DONOHOE; R FINN; R B MCCONNELL; P M SHEPPARD; D LEHANE; S H RUSSELL; W KULKE; C M DURKIN
Journal:  Br Med J       Date:  1965-01-30

2.  Antepartum management of Rh hemolytic disease.

Authors:  V J FREDA; J G GORMAN
Journal:  Bull Sloane Hosp Women Columbia Presbyt Med       Date:  1962

3.  A one-stage factor VIII (antihaemophilic globulin) assay and its use on venous and capillary plasma.

Authors:  R M HARDISTY; J C MACPHERSON
Journal:  Thromb Diath Haemorrh       Date:  1962-05-15

4.  Experimental studies on the prevention of Rh haemolytic disease.

Authors:  R FINN; C A CLARKE; W T DONOHOE; R B McCONNELL; P M SHEPPARD; D LEHANE; W KULKE
Journal:  Br Med J       Date:  1961-05-27

5.  The effect of cryoprecipitate concentrate in patients with classical haemophilia.

Authors:  K E Barrett; M C Israëls; A M Burn
Journal:  Lancet       Date:  1967-01-28       Impact factor: 79.321

6.  Production of high-potency concentrates of antihemophilic globulin in a closed-bag system.

Authors:  J G Pool; A E Shannon
Journal:  N Engl J Med       Date:  1965-12-30       Impact factor: 91.245

7.  Dose of anti-D gamma-globulin in prevention of Rh-haemolytic disease of the newborn.

Authors:  C A Clarke; R Finn; D Lehane; R B McConnell; P M Sheppard; J C Woodrow
Journal:  Br Med J       Date:  1966-01-22

8.  The factor-8 activity in fresh and stored plasma.

Authors:  A E Preston
Journal:  Br J Haematol       Date:  1967-01       Impact factor: 6.998

9.  Treatment of haemophilia (factor-8 deficiency) with human antihaemophilic factor prepared by the cryoprecipitate process.

Authors:  C R Prentice; R T Breckenridge; W B Forman; O D Ratnoff
Journal:  Lancet       Date:  1967-03-04       Impact factor: 79.321

  9 in total

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