| Literature DB >> 497111 |
P A Jennings, M F Lavin, D J Hughes, P B Spradbrow.
Abstract
The presence of ocular squamous-cell carcinomas in cattle was associated with significantly lower blastogenic response of peripheral-blood cultures to PHA than that of age-matched control cattle. The difference in blastogenic response was more marked when the external diameter of the tumour exceeded 2 cm. Cattle with aquamous-cell carcinomas had cell-mediated immunity against tumour extracts, as measured by the leucocyte adherence inhibition (LAI) microassay. The LAI reaction against tumour extracts was directly proportional to the general level of cell-mediated immunity as demonstrated by the lymphoproliferative response to PHA.Entities:
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Year: 1979 PMID： 497111 PMCID： PMC2010090 DOI： 10.1038/bjc.1979.226
Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640