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Literature DB >> 4963784

Kinetics and immunoglobulin nature of the antibody response to Mycobacterium tuberculosis.

Abstract

Antibody production after injection of Mycobacterium tuberculosis was studied by use of the single cell plaque assay technique. Maximal numbers of antibody-forming cells were found 9 days after a single injection of M. tuberculosis, about 1 day before the appearance of maximal circulating antibody. Immunoelectrophoretic studies and 2-ME studies on 19S and 7S globulin fractions obtained by gel filtration show that the hemagglutination and hemagglutination-lysis antibody activity is associated with 19S immunoglobulin.

Entities: Chemical Species

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Year: 1967 PMID： 4963784 PMCID： PMC276737 DOI： 10.1128/jb.94.4.815-820.1967

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

18 in total

1. OBSERVATIONS ON THE ANTIBODY RESPONSE OF RABBITS TO MYCOBACTERIAL ANTIGENS.

Authors: T M DANIEL
Journal: J Immunol Date: 1965-07 Impact factor: 5.422

2. Ontogeny of the immune response. I. Development of immunoglobulins in germfree and conventional colostrum-deprived piglets.

Authors: Y B Kim; S G Bradley; D W Watson
Journal: J Immunol Date: 1966-07 Impact factor: 5.422

3. Ontogeny of the immune response. II. Characterization of 19S-gamma-G- and 7S-gamma-G-immunoglobulins in the true primary and secondary responses in piglets.

Authors: Y B Kim; S G Bradley; D W Watson
Journal: J Immunol Date: 1966-08 Impact factor: 5.422

4. Studies on heterologous anti-lymphocyte serum in mice. I. In vitro and in vivo properties.

Authors: J G Gray; A P Monaco; M L Wood; P S Russell
Journal: J Immunol Date: 1966-02 Impact factor: 5.422

5. 19S antibody production against soluble lipopolysaccharide antigens by individual lymphoid cells in vitro.

Authors: G Möller
Journal: Nature Date: 1965-09-11 Impact factor: 49.962

6. IgM and IgG anti-hapten antibody: hemolytic, hemagglutinating and precipitating activity.

Authors: K Onoue; N Tanigaki; Y Yagi; D Pressman
Journal: Proc Soc Exp Biol Med Date: 1965-11

7. Immunochemical properties of human gamma-A isohemagglutinin. I. Comparisons with gamma-G and gamma-M-globulin antibodies.

Authors: K Ishizaka; T Ishizaka; E H Lee; H Fudenberg
Journal: J Immunol Date: 1965-08 Impact factor: 5.422

Kinetics and immunoglobulin nature of the antibody response to Mycobacterium tuberculosis.

1. OBSERVATIONS ON THE ANTIBODY RESPONSE OF RABBITS TO MYCOBACTERIAL ANTIGENS.

2. Ontogeny of the immune response. I. Development of immunoglobulins in germfree and conventional colostrum-deprived piglets.

3. Ontogeny of the immune response. II. Characterization of 19S-gamma-G- and 7S-gamma-G-immunoglobulins in the true primary and secondary responses in piglets.

4. Studies on heterologous anti-lymphocyte serum in mice. I. In vitro and in vivo properties.

5. 19S antibody production against soluble lipopolysaccharide antigens by individual lymphoid cells in vitro.

6. IgM and IgG anti-hapten antibody: hemolytic, hemagglutinating and precipitating activity.

7. Immunochemical properties of human gamma-A isohemagglutinin. I. Comparisons with gamma-G and gamma-M-globulin antibodies.

8. Number of binding sites of rabbit macroglobulin antibody and its subunits.

9. Molecular characterization of the antibody response in rabbits to intravenously injected BCG.

10. ANTIBODY SYNTHESIS AT THE CELLULAR LEVEL. ANTIBODY-INDUCED SUPPRESSION OF 19S AND 7S ANTIBODY RESPONSE.

1. Universal occurrence of antibodies to tubercle bacilli in sera from non-tuberculous and tuberculous individuals.