| Literature DB >> 4959256 |
D A Booth, H Goodwin, J N Cumings.
Abstract
The molar ratios of N-acetyl neuraminic acid, hexose, hexosamine, and sphingosine have been determined for the abnormal ganglioside in Tay-Sachs disease that was previously detected as a fast-moving band in thin-layer chromatography, and in two abnormal fast-moving bands of gangliosides from the cortex and white matter of the brain in cases of gargoylism and Niemann-Pick's disease. The fastest-moving ganglioside band in these two conditions contains neither hexosamine nor glucose.Entities:
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Year: 1966 PMID： 4959256
Source DB: PubMed Journal: J Lipid Res ISSN： 0022-2275 Impact factor: 5.922