Literature DB >> 495552

Folacin and iron status and hematological findings in predominately black elderly persons from urban low-income households.

L B Bailey, P A Wagner, G J Christakis, P E Araujo, H Appledorf, C G Davis, J Masteryanni, J S Dinning.   

Abstract

The folacin and iron status and hemotological parameters of 193 persons 60 years of age and older from urban low-income households were evaluated. Of the serum folacin values 30% were between 3 and 6 ng/ml and 8% were below 3 ng/ml. Of these subjects 60% could be classified as "high risk" (less than 140 ng/ml) and 11% as "medium risk" (140 to 160 ng/ml) based on red blood cell folacin concentrations. Serum iron was normal (greater than 50 micrograms/dl) for all subjects as was transferrin saturation (greater than 15%). Hematological indices showed a 14% incidence of anemia (hemaglobin less than 12 g/dl), and 32% incidence of leukopenia (leukocytes less than 4.8 X 10(3)). These findings demonstrate widespread folacin deficiency and no evidence of iron deficiency in these elderly people.

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Year:  1979        PMID: 495552     DOI: 10.1093/ajcn/32.11.2346

Source DB:  PubMed          Journal:  Am J Clin Nutr        ISSN: 0002-9165            Impact factor:   7.045


  4 in total

1.  Cytogenetic damage induced by folate deficiency in mice is enhanced by caffeine.

Authors:  J T MacGregor; R Schlegel; C M Wehr; P Alperin; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

Review 2.  The causes and prevention of cancer.

Authors:  B N Ames; L S Gold; W C Willett
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-06       Impact factor: 11.205

3.  Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage.

Authors:  B C Blount; M M Mack; C M Wehr; J T MacGregor; R A Hiatt; G Wang; S N Wickramasinghe; R B Everson; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-01       Impact factor: 11.205

Review 4.  The causes and prevention of cancer: gaining perspective.

Authors:  B N Ames; L S Gold
Journal:  Environ Health Perspect       Date:  1997-06       Impact factor: 9.031

  4 in total

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