Literature DB >> 495143

The analgesic action of some flavonoids in the hot plate test.

M Rylski, H Duriasz-Rowińska, W Rewerski.   

Abstract

Albino-Swiss male mice were tested in the hot plate test. Oligomeric procyjanidin (OL-1), rutin, quercetin, hyperoside and vitexin rhamnoside were administered intraperitoneally in doses 3.5 and 10 mg/kg. It was found that OL-1, rutin and hyperoside but not vitexin rhamnoside exert analgesic action, whereas quercetin even decreases the pain threshold level. The mechanism of the analgesic action of flavonoids remains to be explained.

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Year:  1979        PMID： 495143     DOI： 10.103/00006450-01000-0000

Source DB:  PubMed          Journal:  Acta Physiol Pol        ISSN： 0044-6033


  8 in total

1.  Hyperoside Suppresses Lipopolysaccharide-induced Inflammation and Apoptosis in Human Umbilical Vein Endothelial Cells.

Authors:  Yan-Qiang Zhou; Yin-Tao Zhao; Xiao-Yan Zhao; Cui Liang; Ya-Wei Xu; Ling Li; Yuan Liu; Hai-Bo Yang
Journal:  Curr Med Sci       Date:  2018-04-30

2.  Hyperoside induces apoptosis and inhibits growth in pancreatic cancer via Bcl-2 family and NF-κB signaling pathway both in vitro and in vivo.

Authors:  Yilong Li; Yongwei Wang; Le Li; Rui Kong; Shangha Pan; Liang Ji; Huan Liu; Hua Chen; Bei Sun
Journal:  Tumour Biol       Date:  2015-12-16

3.  Analgesic effects of a standardized bioflavonoid composition from Scutellaria baicalensis and Acacia catechu.

Authors:  Mesfin Yimam; Lidia Brownell; Mandee Hodges; Qi Jia
Journal:  J Diet Suppl       Date:  2012-08-10

4.  Phytochemical Screening and Evaluation of Analgesic Activity of Oroxylum indicum.

Authors:  B K Das; M M Al-Amin; S M Russel; S Kabir; R Bhattacherjee; J M A Hannan
Journal:  Indian J Pharm Sci       Date:  2014 Nov-Dec       Impact factor: 0.975

Review 5.  The Pharmacological Potential of Rutin.

Authors:  Aditya Ganeshpurkar; Ajay K Saluja
Journal:  Saudi Pharm J       Date:  2016-04-30       Impact factor: 4.330

6.  A role of periaqueductal grey NR2B-containing NMDA receptor in mediating persistent inflammatory pain.

Authors:  Jing Hu; Zhe Wang; Yan-Yan Guo; Xiao-Nan Zhang; Zhao-Hui Xu; Shui-Bing Liu; Hong-Ju Guo; Qi Yang; Fu-Xing Zhang; Xiao-Li Sun; Ming-Gao Zhao
Journal:  Mol Pain       Date:  2009-12-12       Impact factor: 3.395

7.  Antioxidant, Antinociceptive and CNS Activities of Viscum orientale and High Sensitive Quantification of Bioactive Polyphenols by UPLC.

Authors:  Amina Khatun; Mahmudur Rahman; Md Mahfizur Rahman; Hemayet Hossain; Ismet A Jahan; Mst Luthfun Nesa
Journal:  Front Pharmacol       Date:  2016-06-29       Impact factor: 5.810

8.  The Anti-Inflammatory and the Antinociceptive Effects of Mixed Agrimonia pilosa Ledeb. and Salvia miltiorrhiza Bunge Extract.

Authors:  Jing-Hui Feng; Hyun-Yong Kim; Su-Min Sim; Guang-Lei Zuo; Jeon-Sub Jung; Seung-Hwan Hwang; Youn-Gil Kwak; Min-Jung Kim; Jeong-Hun Jo; Sung-Chan Kim; Soon-Sung Lim; Hong-Won Suh
Journal:  Plants (Basel)       Date:  2021-06-17
  8 in total

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