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Literature DB >> 4951151

Immunoglobulin A: localization in rectal mucosal epithelial cells.

Abstract

Immunofluorescence studies with monospecific antiserums to human serum immunoglobulins consistently revealed immunoglobulin A within the apical portion of the cytoplasm of rectal mucosal epithelial cells in normal subjects, as well as in patients with various bowel diseases. Immunoglobulins M, G, and D were not demonstrated within mucosal epithelial cells. The predominance of lymphoid cells containing immunoglobulin A in the lamina propria of intestinal tissues was confirmed.

Entities: Disease Species

Mesh：

Substances：
Immunoglobulin A

Year: 1967 PMID： 4951151 DOI： 10.1126/science.157.3791.930

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

10 in total

Review 1. Immunoglobulins and the gut.

Authors: E A Jones
Journal: Gut Date: 1972-10 Impact factor: 23.059

Review 2. The demonstration and function of antibodies in the gastrointestinal tract.

Authors: D J Shearman; D M Parkin; D B McClelland
Journal: Gut Date: 1972-06 Impact factor: 23.059

3. A clinico-immunological study of ulcerative colitis and ulcerative proctitis.

Authors: A H Smith; I W Macphee
Journal: Gut Date: 1971-01 Impact factor: 23.059

4. In vitro synthesis of immunoglobulins, secretory component and complement in normal and pathological skin and the adjacent mucous membranes.

Authors: R F Lai a Fat; D Suurmond; R van Furth
Journal: Clin Exp Immunol Date: 1973-07 Impact factor: 4.330

9. An immunofluorescent study of the distribution of immunoglobulin-containing cells in the normal and the inflamed human gall bladder.

Authors: F H Green; H Fox
Journal: Gut Date: 1972-05 Impact factor: 23.059

10. The human secretory immunoglobulin system: immunohistoligical localization of gamma A, secretory "piece," and lactoferrin in normal human tissues.

Authors: D R Tourville; R H Adler; J Bienenstock; T B Tomasi
Journal: J Exp Med Date: 1969-02-01 Impact factor: 14.307

10 in total

Immunoglobulin A: localization in rectal mucosal epithelial cells.

Review 1. Immunoglobulins and the gut.

Review 2. The demonstration and function of antibodies in the gastrointestinal tract.

3. A clinico-immunological study of ulcerative colitis and ulcerative proctitis.

4. In vitro synthesis of immunoglobulins, secretory component and complement in normal and pathological skin and the adjacent mucous membranes.

5. Intestinal secretion of immunoglobulins and antibodies to Escherichia coli in the pig.

6. Serum levels of immunoglobulins in marasmic infants.

7. Progressive changes of Vibrio serotypes in germ-free mice infected with Vibrio cholerae.

8. Immunoglobulin-containing cells in the intestinal mucosa and immunoglobulins in the intestinal juice in children.

9. An immunofluorescent study of the distribution of immunoglobulin-containing cells in the normal and the inflamed human gall bladder.

10. The human secretory immunoglobulin system: immunohistoligical localization of gamma A, secretory "piece," and lactoferrin in normal human tissues.