Literature DB >> 494825

[Forensic aspects of digoxin-poisoning: toxicological and morphological findings (author's transl)].

W Arnold, K Püschel.   

Abstract

Case report. A 82 year old woman died 80 min after accidental ingestion of 5 mg beta-methyl-digoxin. The autopsy and the histological examination revealed non-specific alterations due to shock and preexisting coronary heart disease. Digoxin levels in various fluids and tissues were estimated by radioimmunoassay: bloodplasma 20--25 ng/ml, liquor 10--13 ng/ml, liver 100--110 ng/g, kidney 130--145 ng/g; the gastric fluid contained 0,6 mg. Forensic aspects of glycosid-intoxication, especially of the varying concentrations in different tissues, are discussed.

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Year:  1979        PMID: 494825     DOI: 10.1007/bf02333330

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  22 in total

1.  Correlation of antemortem and postmortem digoxin levels.

Authors:  T E Vorpahl; J I Coe
Journal:  J Forensic Sci       Date:  1978-04       Impact factor: 1.832

2.  Postmortem assay of digoxin by radioimmunoassay.

Authors:  D W Holt; J G Benstead
Journal:  J Clin Pathol       Date:  1975-06       Impact factor: 3.411

3.  [Radioimmunologic determination of glycoside concentrations in human brain tissue].

Authors:  R Haasis; D Larbig
Journal:  Verh Dtsch Ges Kreislaufforsch       Date:  1976

4.  [Accidental digitalis intoxication in small children (author's transl)].

Authors:  M Zach; A Beitzke; H M Grubbauer
Journal:  Padiatr Padol       Date:  1977

5.  Tissue concentrations of digoxin in an autopsy material.

Authors:  J Karjalainen; K Ojala; P Reissell
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1974-05

Review 6.  [Determination of digoxin and digitoxin in the blood and their clinical significance].

Authors:  G Bodem; H J Gilfrich
Journal:  Klin Wochenschr       Date:  1973-01-15

7.  Fatal digitalis poisoning.

Authors:  A Steentoft
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1973

8.  [Detection and identification of cardioactive glycosides in toxicology].

Authors:  W Kisser
Journal:  Arch Toxikol       Date:  1969

9.  Altered tissue digoxin uptake after a toxic dose.

Authors:  K Taubert; W Shapiro
Journal:  Recent Adv Stud Cardiac Struct Metab       Date:  1975

10.  [Digoxin and beta-methyldigoxin concentrations in cerebrospinal fluid and plasma (author's transl)].

Authors:  G Bodem; U Boldt; H Ochs
Journal:  Klin Wochenschr       Date:  1977-04-01
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  5 in total

1.  [Interpretation of postmortem digoxin levels: evaluating a "corrective factor" for postmortem blood digoxin concentration].

Authors:  S Ritz; H J Kaatsch
Journal:  Z Rechtsmed       Date:  1990

2.  [Classification of digoxin concentrations in blood and tissues in cases under suspicion of poisoning].

Authors:  W Härdle; R Aderjan
Journal:  Z Rechtsmed       Date:  1983

3.  LC-MS assay for quantitative determination of cardio glycoside in human blood samples.

Authors:  L Frommherz; H Köhler; B Brinkmann; M Lehr; J Beike
Journal:  Int J Legal Med       Date:  2007-06-14       Impact factor: 2.686

4.  Measurement of digitalis-glycoside levels in ocular tissues: a way to improve postmortem diagnosis of lethal digitalis-glycoside poisoning? I. Digoxin.

Authors:  S Ritz; P Harding; W Martz; H W Schütz; H J Kaatsch
Journal:  Int J Legal Med       Date:  1992       Impact factor: 2.686

5.  Serum levels of digoxin in sudden cardiac deaths.

Authors:  M Eriksson; O Lindquist; B Edlund
Journal:  Z Rechtsmed       Date:  1984
  5 in total

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