Literature DB >> 4946617

Principles and practice of Hansch analysis: a guide to structure-activity correlation for the medicinal chemist.

M S Tute.   

Abstract

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Year:  1971        PMID： 4946617

Source DB:  PubMed          Journal:  Adv Drug Res        ISSN： 0065-2490


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  14 in total

1.  Determination of receptor-bound drug conformations by QSAR using flexible fitting to derive a molecular similarity index.

Authors:  C A Montanari; M S Tute; A E Beezer; J C Mitchell
Journal:  J Comput Aided Mol Des       Date:  1996-02       Impact factor: 3.686

2.  Relationships between chemical structure and affinity for postganglionic acetylcholine receptors of the guinea-pig ileum.

Authors:  F B Abramson; R B Barlow; F M Franks; J D Pearson
Journal:  Br J Pharmacol       Date:  1974-05       Impact factor: 8.739

3.  Time-independent effects on cardiac action potential upstroke velocity (resting block) and lipid solubility of beta adrenergic blockers.

Authors:  H Sada; T Ban
Journal:  Experientia       Date:  1981-02-15

4.  Structure-activity studies on nifedipine in isolated cardiac muscle.

Authors:  R Rodenkirchen; R Bayer; R Steiner; F Bossert; H Meyer; E Möller
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-12       Impact factor: 3.000

5.  Measurement of hydrophobicity, surface activity, local anaesthesia, and myocardial conduction velocity as quantitative parameters of the non-specific membrane affinity of nine -adrenergic blocking agents.

Authors:  D Hellenbrecht; B Lemmer; G Wiethold; H Grobecker
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

6.  Correlation between the negative inotropic potency and binding parameters of 1,4-dihydropyridine and phenylalkylamine calcium channel blockers in cat heart.

Authors:  A Goll; H Glossmann; R Mannhold
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-11       Impact factor: 3.000

7.  Inhibition of Bacillus subtilis spore germination by various hydrophobic compounds: demonstration of hydrophobic character of the L-alanine receptor site.

Authors:  Y Yasuda-Yasaki; S Namiki-Kanie; Y Hachisuka
Journal:  J Bacteriol       Date:  1978-11       Impact factor: 3.490

8.  Modeling biophysical and biological properties from the characteristics of the molecular electron density, electron localization and delocalization matrices, and the electrostatic potential.

Authors:  Chérif F Matta
Journal:  J Comput Chem       Date:  2014-04-29       Impact factor: 3.376

9.  Development of a preformulation lipophilicity screen utilizing a C-18-derivatized polystyrene-divinylbenzene high-performance liquid chromatographic (HPLC) column.

Authors:  W J Lambert; L A Wright; J K Stevens
Journal:  Pharm Res       Date:  1990-06       Impact factor: 4.200

10.  The specificity of some agonists and antagonists for nicotine-sensitive receptors in ganglia.

Authors:  R B Barlow; F Bowman; R R Ison; D S McQueen
Journal:  Br J Pharmacol       Date:  1974-08       Impact factor: 8.739
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