Literature DB >> 494494

Tumor-specific transplantation and surface antigen in cells transformed by the adenovirus 12 DNA fragments.

K Shiroki1, H Shimojo, Y Maeta, C Hamada.   

Abstract

Adenovirus type 12 (Ad 12) tumor-specific transplantation antigen (TSTA) and the surface (S) antigen were examined using rat cells transformed with Ad 12 DNA and its fragments. WY3 (3Yl cells transformed with Ad 12 whole DNA), CYl (3Yl cells transformed with the EcoRI-C fragment of Ad 12 DNA), and GY cells (3Yl cells transformed with the HindIII-G fragment of Ad 12 DNA) contained TSTA and S antigen, but HY cells (3Y1 cells transformed with the BpaI-H fragment of Ad12 DNA) did not. These results suggest that TSTA and S antigens contain a protein(s) coded for by a portion of the transforming gene.

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Year:  1979        PMID： 494494     DOI： 10.1016/0042-6822(79)90053-9

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  3 in total

1.  Dependence of tumor-forming capacities of cells transformed by recombinants between adenovirus types 5 and 12 on expression of early region 1.

Authors:  K Shiroki; K Maruyama; I Saito; Y Fukui; K Yazaki; H Shimojo
Journal:  J Virol       Date:  1982-05       Impact factor: 5.103

2.  Deletion of the gene encoding the adenovirus 5 early region 1b 21,000-molecular-weight polypeptide leads to degradation of viral and host cell DNA.

Authors:  S Pilder; J Logan; T Shenk
Journal:  J Virol       Date:  1984-11       Impact factor: 5.103

3.  Expression of the adenovirus E1A oncogene during cell transformation is sufficient to induce susceptibility to lysis by host inflammatory cells.

Authors:  J L Cook; T A Walker; A M Lewis; H E Ruley; F L Graham; S H Pilder
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205
  3 in total

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