Literature DB >> 4943214

Response of HL-A identical unrelated individuals in the mixed lymphocyte culture test.

J M Johnston, H V Bashir.   

Abstract

The immunological responsiveness as measured in the mixed lymphocyte culture test has been studied in 13 pairs of HL-A identical unrelated individuals. In all combinations stimulation occurred and it was frequently of a similar magnitude to that observed against non-HL-A identical subjects.It is postulated that another locus, adjacent to the HL-A locus, is also responsible for the non-stimulation observed between HL-A identical siblings, and that observations made in the related situation should not be transposed to the unrelated situation without some reservation.

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Year:  1971        PMID： 4943214      PMCID： PMC1799948          DOI： 10.1136/bmj.4.5787.581

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  8 in total

1.  The HL-A system: antigenic heterogeneity and four new antigens.

Authors:  E Thorsby; A Bratlie; W Mayr; J Sparck; A Svejgaard; K E Kjerbye; F Kissmeyer-Nielsen
Journal:  Tissue Antigens       Date:  1971

2.  Critical evaluation of histocompatibility in 179 renal transplants.

Authors:  J Hors; N Feingold; D Fradelizi; J Dausset
Journal:  Lancet       Date:  1971-03-27       Impact factor: 79.321

3.  Histocompatibility matching. V. A comparison of typing and mixed cultures in unrelated individuals.

Authors:  F H Bach; E Day; M L Bach; B A Myhre; D P Sengar; P I Terasaki
Journal:  Tissue Antigens       Date:  1971

4.  Mixed lymphocyte cultures and HL-A identity in unrelated subjects.

Authors:  F Kissmeyer-Nielsen; A Svejgaard; S F Sorensen; L S Nielsen; E Thorsby
Journal:  Nature       Date:  1970-10-03       Impact factor: 49.962

5.  HL-A identical phenotypes and genotypes in unrelated individuals.

Authors:  J J van Rood; V P Eijsvoogel
Journal:  Lancet       Date:  1970-04-04       Impact factor: 79.321

Review 6.  Transplantation: pairing of donor and recipient.

Authors:  F H Bach
Journal:  Science       Date:  1970-06-05       Impact factor: 47.728

7.  Studies on the HL-A antigens of human lymphocytes: inheritance in clusters.

Authors:  A M Sharp; K M Cook; J M Johnston
Journal:  Nature       Date:  1970-08-29       Impact factor: 49.962

8.  Phenotypic expressions of the major histocompatibility locus in man (HL-A): leukocyte antigens and mixed leukocyte culture reactivity.

Authors:  D B Amos; F H Bach
Journal:  J Exp Med       Date:  1968-10-01       Impact factor: 14.307
  8 in total
  2 in total

1.  The interaction of normal lymphocytes nd cells from lymphoid cell lines. 3. Studies on activation in an autochthonous system.

Authors:  C M Steel; D A Hardy; N R Ling; H M Dick; P Mackintosh; W B Crichton
Journal:  Immunology       Date:  1973-01       Impact factor: 7.397

2.  Observations upon DNA synthesis and the cytotoxic response of leucocytes after mixed culture and their relation to histocompatibility antigens in man.

Authors:  G D Pegrum; C A Evans; V L Middleton; I C Balfour
Journal:  Clin Exp Immunol       Date:  1972-11       Impact factor: 4.330
  2 in total

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