Literature DB >> 4943176

DNA replication in Escherichia coli: location of recently incorporated thymidine within molecules of high molecular weight DNA.

V N Iyer, K G Lark.   

Abstract

More than 50% of the [(3)H]thymidine incorporated during short pulses into the DNA of Escherichia coli 15T(-) can be extracted by alkali as high molecular weight DNA. Density gradient centrifugation and digestion with exonuclease I suggest that these large pieces of DNA are composed of newly synthesized DNA attached to pre-existing material at the 3' end of the molecule.

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Year:  1970        PMID: 4943176      PMCID: PMC283252          DOI: 10.1073/pnas.67.2.629

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  17 in total

1.  Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli: a new enzyme.

Authors:  H V APOSHIAN; A KORNBERG
Journal:  J Biol Chem       Date:  1962-02       Impact factor: 5.157

Review 2.  Enzymes in DNA metabolism.

Authors:  C C Richardson
Journal:  Annu Rev Biochem       Date:  1969       Impact factor: 23.643

3.  Isolation of an E. coli strain with a mutation affecting DNA polymerase.

Authors:  P De Lucia; J Cairns
Journal:  Nature       Date:  1969-12-20       Impact factor: 49.962

4.  Chromosome replication in Escherichia coli 15T- at different growth rates: rate of replication of the chromosome and the rate of formation of small pieces.

Authors:  R E Bird; K G Lark
Journal:  J Mol Biol       Date:  1970-04-28       Impact factor: 5.469

5.  Discontinuous synthesis of DNA during replication.

Authors:  A Yudelevich; B Ginsberg; J Hurwitz
Journal:  Proc Natl Acad Sci U S A       Date:  1968-11       Impact factor: 11.205

6.  Initiation and propagation of growing points in the DNA of phage T4.

Authors:  R Werner
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1968

7.  DNA replication: the rolling circle model.

Authors:  W Gilbert; D Dressler
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1968

8.  Mechanism of DNA chain growth. 3. Equal annealing of T4 nascent short DNA chains with the separated complementary strands of the phage DNA.

Authors:  K Sugimoto; T Okazaki; Y Imae; R Okazaki
Journal:  Proc Natl Acad Sci U S A       Date:  1969-08       Impact factor: 11.205

9.  DNA replication in mammalian cells. I. The size of newly synthesized helices.

Authors:  F Nuzzo; A Brega; A Falaschi
Journal:  Proc Natl Acad Sci U S A       Date:  1970-04       Impact factor: 11.205

10.  Mechanism of DNA chain growth. IV. Direction of synthesis of T4 short DNA chains as revealed by exonucleolytic degradation.

Authors:  T Okazaki; R Okazaki
Journal:  Proc Natl Acad Sci U S A       Date:  1969-12       Impact factor: 11.205

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  3 in total

1.  Regions of single-stranded DNA in the growing points of replicating bacteriophage T7 chromosomes.

Authors:  J Wolfson; D Dressler
Journal:  Proc Natl Acad Sci U S A       Date:  1972-09       Impact factor: 11.205

2.  Size distribution and molecular polarity of newly replicated DNA in Escherichia coli.

Authors:  J M Louarn; R E Bird
Journal:  Proc Natl Acad Sci U S A       Date:  1974-02       Impact factor: 11.205

Review 3.  Repriming DNA synthesis: an intrinsic restart pathway that maintains efficient genome replication.

Authors:  Lewis J Bainbridge; Rebecca Teague; Aidan J Doherty
Journal:  Nucleic Acids Res       Date:  2021-05-21       Impact factor: 16.971

  3 in total

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