Literature DB >> 494228

Further evidence for independent segregation of the HLA system and a structural gene for the sixth component of complement (C6).

E Kagan, G M Maier, G T Nurse, K Miller, A R Rabson.   

Abstract

Previous studies have shown conflicting results with respect to the relationship between C6 deficiency and the HLA system. The present investigation of two kinships, in which C6 deficiency was associated with the expression of an amorphic (or silent) C6 allele, has provided further evidence for the genetic independence of a structural C6 locus and the HLA system.

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Year:  1979        PMID： 494228     DOI： 10.1111/j.1399-0039.1979.tb00816.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN： 0001-2815


  1 in total

1.  Inherited deficiency of C8 in a patient with recurrent meningococcal infections: further evidence for a dysfunctional C8 molecule and nonlinkage to the HLA system.

Authors:  P Densen; E J Brown; G J O'Neill; F Tedesco; R A Clark; M M Frank; D Webb; J Myers
Journal:  J Clin Immunol       Date:  1983-01       Impact factor: 8.317
  1 in total

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