Literature DB >> 493995

Noncycling tumor cells are sensitive targets for the antiproliferative activity of human interferon.

J S Horoszewicz, S S Leong, W A Carter.   

Abstract

Resting Burkitt's lymphoma cells (Daudi) in culture are more sensitive targets for the antiproliferative activity of purified human fibroblast interferon than cells that are rapidly multiplying. Thus, interferon may be of significant clinical value in neoplasms involving stem cells and, after chemotherapy, in suppressing the reemergence of tumors.

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Year:  1979        PMID： 493995     DOI： 10.1126/science.493995

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

Review 1.  Interferons: current status and future directions of this prototypic biological.

Authors:  R V Smalley; E C Borden
Journal:  Springer Semin Immunopathol       Date:  1986

2.  Type I interferons induce apoptosis by balancing cFLIP and caspase-8 independent of death ligands.

Authors:  Amir Apelbaum; Ganit Yarden; Shira Warszawski; Daniel Harari; Gideon Schreiber
Journal:  Mol Cell Biol       Date:  2012-12-10       Impact factor: 4.272

3.  Treatment of advanced renal cell cancer with recombinant interferon alpha as a single agent and in combination with medroxyprogesterone acetate. A randomized multicenter trial.

Authors:  F Porzsolt; D Messerer; R Hautmann; A Gottwald; H Sparwasser; K Stockamp; W Aulitzky; J G Moormann; K Schumacher; H Rasche
Journal:  J Cancer Res Clin Oncol       Date:  1988       Impact factor: 4.553

4.  Increased levels of (2'-5')oligo(A) polymerase activity in human lymphoblastoid cells treated with glucocorticoids.

Authors:  I Krishnan; C Baglioni
Journal:  Proc Natl Acad Sci U S A       Date:  1980-11       Impact factor: 11.205

5.  Tumor heterogeneity: biological implications and therapeutic consequences.

Authors:  G H Heppner; B E Miller
Journal:  Cancer Metastasis Rev       Date:  1983       Impact factor: 9.264

6.  Antiproliferative effects of bacillus Calmette-Guerin and interferon alpha 2b on human bladder cancer cells in vitro.

Authors:  K Pryor; P Stricker; P Russell; D Golovsky; R Penny
Journal:  Cancer Immunol Immunother       Date:  1995-11       Impact factor: 6.968

7.  The failure of human leukocyte interferon to influence the growth of human glioma cell populations: in vitro and in vivo studies.

Authors:  N J Bradley; J L Darling; N Oktar; H J Bloom; D G Thomas; A J Davies
Journal:  Br J Cancer       Date:  1983-12       Impact factor: 7.640
  7 in total

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