Literature DB >> 493987

Calcitonin: inhibitory effect on eating in rats.

W J Freed, M J Perlow, R J Wyatt.   

Abstract

Subcutaneous and intracerebral injections of calcitonin inhibited feeding in rats. The anorectic activity of calcitonin was destroyed by exposing the hormone to heat, trypsin, or hydrogen peroxide. Calcitonin did not produce a conditioned taste aversion to saccharin, and maximum inhibition of feeding occurred 4.5 to 8.3 hours after subcutaneous administration. It is concluded that calcitonin inhibits feeding by acting directly on the central nervous system.

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Year:  1979        PMID： 493987     DOI： 10.1126/science.493987

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  14 in total

Review 1.  Pharmacological approaches for the treatment of obesity.

Authors:  José-Antonio Fernández-López; Xavier Remesar; Màrius Foz; Marià Alemany
Journal:  Drugs       Date:  2002       Impact factor: 9.546

Review 2.  Appetite regulation: the role of peptides and hormones.

Authors:  J E Morley
Journal:  J Endocrinol Invest       Date:  1989-02       Impact factor: 4.256

3.  The effect of high-dose salmon calcitonin on bone mineral metabolism in the normal rat.

Authors:  N Glajchen; S Thomas; P Jowell; S Epstein; F Ismail; M Fallon
Journal:  Calcif Tissue Int       Date:  1990-01       Impact factor: 4.333

4.  Effects of calcitonin on human auditory and visual evoked brain potentials.

Authors:  R Pietrowsky; M Dentler; H L Fehm; J Born
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

Review 5.  A step towards developing the expertise to control hunger and satiety: regulatory role of satiomem--a membrane proteoglycan.

Authors:  R K Upreti; A M Kidwai
Journal:  Neurochem Res       Date:  1995-04       Impact factor: 3.996

Review 6.  Satietin; a 50,000 dalton glycoprotein in human serum with potent, long-lasting and selective anorectic activity.

Authors:  J Knoll
Journal:  J Neural Transm       Date:  1984       Impact factor: 3.575

7.  Satietin, a blood-borne anorectic glycoprotein, as the putative rate-limiting satiety signal in the negative feed-back of food intake.

Authors:  J Knoll
Journal:  Z Ernahrungswiss       Date:  1984-06

8.  Immunoreactive calcitonin in brain regions and pituitary of sheep.

Authors:  S Balabanova; O King; R Nowak; H Sachs; D Leupold
Journal:  J Endocrinol Invest       Date:  1985-10       Impact factor: 4.256

9.  Calcitonin: regional distribution of the hormone and its binding sites in the human brain and pituitary.

Authors:  J A Fischer; P H Tobler; M Kaufmann; W Born; H Henke; P E Cooper; S M Sagar; J B Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

10.  Inhibition of restraint stress by systemic (Asu1,7) eel-calcitonin.

Authors:  G Clementi; A Prato; E Rapisarda; G Conforto; O Mangano; A Caruso; U Scapagnini
Journal:  J Endocrinol Invest       Date:  1985-12       Impact factor: 4.256
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