Literature DB >> 493979

Molecular microanalysis of pathological specimens in situ with a laser-Raman microprobe.

J L Abraham, E S Etz.   

Abstract

A laser-Raman microprobe has been used to identify microscopic inclusions of silicone polymer in standard paraffin sections of lymph node. This example of organic chemical microanalysis in situ in pathological tissue represents an extension of microanalytical capabilities from elemental analysis, performed with electron and ion microprobes, to compound-specific molecular microanalysis.

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Year:  1979        PMID： 493979     DOI： 10.1126/science.493979

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  8 in total

Review 1.  Coherent Raman Scattering Microscopy in Biology and Medicine.

Authors:  Chi Zhang; Delong Zhang; Ji-Xin Cheng
Journal:  Annu Rev Biomed Eng       Date:  2015-10-22       Impact factor: 9.590

2.  Why are blue visual pigments blue? A resonance Raman microprobe study.

Authors:  G R Loppnow; B A Barry; R A Mathies
Journal:  Proc Natl Acad Sci U S A       Date:  1989-03       Impact factor: 11.205

3.  In Situ and In Vivo Molecular Analysis by Coherent Raman Scattering Microscopy.

Authors:  Chien-Sheng Liao; Ji-Xin Cheng
Journal:  Annu Rev Anal Chem (Palo Alto Calif)       Date:  2016-06-12       Impact factor: 10.745

4.  Insights and prospects for ion mobility-mass spectrometry in clinical chemistry.

Authors:  David C Koomen; Jody C May; John A McLean
Journal:  Expert Rev Proteomics       Date:  2022-01-17       Impact factor: 3.940

Review 5.  Spectroscopic Imaging at the Nanoscale: Technologies and Recent Applications.

Authors:  Lifu Xiao; Zachary D Schultz
Journal:  Anal Chem       Date:  2017-10-27       Impact factor: 6.986

Review 6.  New techniques for imaging and analyzing lung tissue.

Authors:  V L Roggli; P Ingram; R W Linton; W F Gutknecht; P Mastin; J D Shelburne
Journal:  Environ Health Perspect       Date:  1984-06       Impact factor: 9.031

7.  Saliva-based detection of COVID-19 infection in a real-world setting using reagent-free Raman spectroscopy and machine learning.

Authors:  Katherine Ember; François Daoust; Myriam Mahfoud; Frédérick Dallaire; Esmat Zamani Ahmad; Trang Tran; Arthur Plante; Mame-Kany Diop; Tien Nguyen; Amélie St-Georges-Robillard; Nassim Ksantini; Julie Lanthier; Antoine Filiatrault; Guillaume Sheehy; Gabriel Beaudoin; Caroline Quach; Dominique Trudel; Frédéric Leblond
Journal:  J Biomed Opt       Date:  2022-02       Impact factor: 3.758

8.  A Wide-Field Imaging Approach for Simultaneous Super-Resolution Surface-Enhanced Raman Scattering Bioimaging and Spectroscopy.

Authors:  Deben N Shoup; Brian T Scarpitti; Zachary D Schultz
Journal:  ACS Meas Sci Au       Date:  2022-04-27
  8 in total

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