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Literature DB >> 4938432

Trimethoprim and sulphamethoxazole in typhoid fever in children.

Abstract

One hundred and three children with proved typhoid fever were treated with trimethoprim-sulphamethoxazole, and the results compared with those of a further 40 children treated with chloramphenicol. The bacteriological response to trimethoprim-sulphamethoxazole was unsatisfactory. From this study it seems that at present chloramphenicol is still the treatment of choice for typhoid fever. In view of the haematological changes occurring during therapy with trimethoprim-sulphamethoxazole caution is necessary and monitoring of the blood picture advisable, even at the recommended dose.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1971 PMID： 4938432 PMCID： PMC1798935 DOI： 10.1136/bmj.3.5777.738

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

8 in total

Review 1. Typhoid fever in African and Indian children in Durban.

Authors: J Scragg; C Rubidge; H L Wallace
Journal: Arch Dis Child Date: 1969-02 Impact factor: 3.791

2. Drug neutropenia.

Authors: J W Paulley
Journal: Br Med J Date: 1970-05-09

3. Trimethoprim-sulphamethoxazole in typhoid.

Authors: A C Wicks; T J Stamps
Journal: Br Med J Date: 1970-10-03

4. Agranulocytosis after trimethoprim and sulphamethoxazole.

Authors: D I Evans; R Tell
Journal: Br Med J Date: 1969-03-01

5. Thrombocytopenia and agranulocytosis following "septrin".

Authors: P Mohan
Journal: Practitioner Date: 1969-04

6. Trimethoprim-sulphamethoxazole in enteric fevers.

Authors: Z Farid; A Hassan; M F Wahab; W R Sanborn; D C Kent; S E Hathout
Journal: Br Med J Date: 1970-08-08

7. Evaluation of therapeutic efficacy of trimethoprim-sulphamethoxazole and chloramphenicol in enteric fever.

Authors: S A Kamat
Journal: Br Med J Date: 1970-08-08

8. Trimethoprim and sulphamethoxazole in typhoid.

Authors: O O Akinkugbe; E A Lewis; D Montefiore; O A Okubadejo
Journal: Br Med J Date: 1968-09-21

8 in total

19 in total

Review 1. Antibacterial drugs today. I.

Authors: A P Ball; J A Gray; J M Murdoch
Journal: Drugs Date: 1975 Impact factor: 9.546

2. Further experience with amoxycillin in typhoid fever in children.

Authors: J N Scragg
Journal: Br Med J Date: 1976-10-30

3. Serum bactericidal activity of two newer quinolones against Salmonella typhi compared with standard therapeutic regimens.

Authors: M Trautmann; B Krause; D Birnbaum; J Wagner; V Lenk
Journal: Eur J Clin Microbiol Date: 1986-06 Impact factor: 3.267

4. Typhoid fever: treatment failure and multiple relapses with trimethoprim-sulfamethoxazole and chloramphenicol therapy.

Authors: D Portnoy; S Seah
Journal: Can Med Assoc J Date: 1979-05-19 Impact factor: 8.262

10. Lactose-fermenting, multiple drug-resistant Salmonella typhi strains isolated from a patient with postoperative typhoid fever.

Authors: S Kohbata; M Takahashi; E Yabuuchi
Journal: J Clin Microbiol Date: 1983-10 Impact factor: 5.948